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1T04

Three dimensional structure of a humanized anti-IFN-Gamma Fab in C2 space group

Summary for 1T04
Entry DOI10.2210/pdb1t04/pdb
Related1B2W 1B4J
DescriptorHuzaf Antibody Light Chain, Huzaf Antibody Heavy Chain (3 entities in total)
Functional Keywordsantibody engineering, humanized and chimeric antibody, fab, three-dimensional structure, gamma-interferon, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight93616.07
Authors
Bourne, P.C.,Terzyan, S.S.,Cloud, G.,Landolfi, N.F.,Vasquez, M.,Edmundson, A.B. (deposition date: 2004-04-07, release date: 2004-10-05, Last modification date: 2023-08-23)
Primary citationBourne, P.C.,Terzyan, S.S.,Cloud, G.,Landolfi, N.F.,Vasquez, M.,Edmundson, A.B.
Three-dimensional structures of a humanized anti-IFN-gamma Fab (HuZAF) in two crystal forms.
Acta Crystallogr.,Sect.D, 60:1761-1769, 2004
Cited by
PubMed: 15388922
DOI: 10.1107/S0907444904018670
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

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