1RWK
Crystal structure of human caspase-1 in complex with 3-(2-mercapto-acetylamino)-4-oxo-pentanoic acid
Summary for 1RWK
Entry DOI | 10.2210/pdb1rwk/pdb |
Related | 1bmq 1ibc 1ice 1rwm 1rwn 1rwo 1rwp 1rwv 1rww 1rwx |
Descriptor | Interleukin-1 beta convertase, 3-(2-MERCAPTO-ACETYLAMINO)-4-OXO-PENTANOIC ACID, ... (4 entities in total) |
Functional Keywords | protein-small molecule inhibitor complex, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P29466 P29466 |
Total number of polymer chains | 2 |
Total formula weight | 30333.83 |
Authors | Romanowski, M.J.,Lam, J.W.,Fahr, B.T.,O'Brien, T. (deposition date: 2003-12-16, release date: 2004-12-28, Last modification date: 2023-08-23) |
Primary citation | O'Brien, T.,Fahr, B.T.,Sopko, M.M.,Lam, J.W.,Waal, N.D.,Raimundo, B.C.,Purkey, H.E.,Pham, P.,Romanowski, M.J. Structural analysis of caspase-1 inhibitors derived from Tethering. Acta Crystallogr.,Sect.F, 61:451-458, 2005 Cited by PubMed: 16511067DOI: 10.1107/S1744309105010109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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