1IBC

CRYSTAL STRUCTURE OF INHIBITED INTERLEUKIN-1BETA CONVERTING ENZYME

Summary for 1IBC

Entry DOI	10.2210/pdb1ibc/pdb
Descriptor	INTERLEUKIN-1BETA CONVERTING ENZYME, PEPTIDE ACE-TRP-GLU-HIS-ASA, ... (4 entities in total)
Functional Keywords	protease, cysteine protease, interleukin-1beta converting enzyme, ice, caspase-1, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: P29466 P29466
Total number of polymer chains	3
Total formula weight	32293.93
Authors	Becker, J.W.,Rotonda, J. (deposition date: 1997-02-12, release date: 1998-02-11, Last modification date: 2024-04-03)
Primary citation	Rano, T.A.,Timkey, T.,Peterson, E.P.,Rotonda, J.,Nicholson, D.W.,Becker, J.W.,Chapman, K.T.,Thornberry, N.A. A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE). Chem.Biol., 4:149-155, 1997 Cited by PubMed: 9190289 DOI: 10.1016/S1074-5521(97)90258-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.73 Å)

Structure validation