1RA6

Poliovirus Polymerase Full Length Apo Structure

1RA6 の概要

• エントリーDOI: 10.2210/pdb1ra6/pdb
• 関連するPDBエントリー: 1RA7 1RAJ 1RDR 1TQL
• 分子名称: Genome polyprotein, ACETIC ACID (3 entities in total)
• 機能のキーワード: nucleotidyltransferase, poliovirus, 3d, rna-dependent, polymerase, n-terminus, transferase
• 由来する生物種: Human poliovirus 1
• 細胞内の位置: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03300
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 53468.27

構造登録者

Thompson, A.A.,Peersen, O.B. (登録日: 2003-10-31, 公開日: 2004-08-17, 最終更新日: 2023-08-23)

• 主引用文献: Thompson, A.A.,Peersen, O.B.; Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.; Embo J., 23:3462-3471, 2004; PubMed: 15306852; DOI: 10.1038/sj.emboj.7600357

実験手法

X-RAY DIFFRACTION (2 Å)