1R0A
Crystal structure of HIV-1 reverse transcriptase covalently tethered to DNA template-primer solved to 2.8 angstroms
Summary for 1R0A
Entry DOI | 10.2210/pdb1r0a/pdb |
Related | 1HYS 1N5Y 1N6Q |
Descriptor | 5'-D(*A*TP*GP*CP*AP*TP*CP*GP*GP*CP*GP*CP*TP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*GP*GP*T)-3', 5'-D(*C*CP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*AP*GP*CP*GP*CP*CP*GP*(2DA))-3', Reverse transcriptase, ... (10 entities in total) |
Functional Keywords | hiv-1, transferase, immune system, dna, transferase-immune system-dna complex, transferase/immune system/dna |
Biological source | Human immunodeficiency virus 1 More |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 P03366 |
Total number of polymer chains | 6 |
Total formula weight | 176881.90 |
Authors | Tuske, S.,Ding, J.,Arnold, E. (deposition date: 2003-09-19, release date: 2004-08-03, Last modification date: 2021-10-27) |
Primary citation | Peletskaya, E.N.,Kogon, A.A.,Tuske, S.,Arnold, E.,Hughes, S.H. Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA. J.Virol., 78:3387-3397, 2004 Cited by PubMed: 15016861DOI: 10.1128/JVI.78.7.3387-3397.2004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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