1NMA

N9 NEURAMINIDASE COMPLEXES WITH ANTIBODIES NC41 AND NC10: EMPIRICAL FREE-ENERGY CALCULATIONS CAPTURE SPECIFICITY TRENDS OBSERVED WITH MUTANT BINDING DATA

1NMA の概要

• エントリーDOI: 10.2210/pdb1nma/pdb
• 分子名称: N9 NEURAMINIDASE, FAB NC10, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: complex (hydrolase-immunoglobulin), complex (hydrolase-immunoglobulin) complex, complex (hydrolase/immunoglobulin)
• 由来する生物種: Influenza A virus; 詳細
• 細胞内の位置: Virion membrane (By similarity): P05803
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 70488.68

構造登録者

Tulip, W.R.,Varghese, J.N.,Colman, P.M. (登録日: 1994-05-06, 公開日: 1995-09-15, 最終更新日: 2020-07-29)

• 主引用文献: Tulip, W.R.,Harley, V.R.,Webster, R.G.,Novotny, J.; N9 neuraminidase complexes with antibodies NC41 and NC10: empirical free energy calculations capture specificity trends observed with mutant binding data.; Biochemistry, 33:7986-7997, 1994; PubMed: 7517697; DOI: 10.1021/bi00192a002

実験手法

X-RAY DIFFRACTION (3 Å)