1NMA
N9 NEURAMINIDASE COMPLEXES WITH ANTIBODIES NC41 AND NC10: EMPIRICAL FREE-ENERGY CALCULATIONS CAPTURE SPECIFICITY TRENDS OBSERVED WITH MUTANT BINDING DATA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| N | 0004308 | molecular_function | exo-alpha-sialidase activity |
| N | 0005975 | biological_process | carbohydrate metabolic process |
| N | 0016020 | cellular_component | membrane |
| N | 0033644 | cellular_component | host cell membrane |
| N | 0046761 | biological_process | viral budding from plasma membrane |
| N | 0055036 | cellular_component | virion membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CsCygEqaGVtC |
| Chain | Residue | Details |
| N | CYS278-CYS289 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04071 |
| Chain | Residue | Details |
| N | ASP151 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_04071 |
| Chain | Residue | Details |
| N | TYR406 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04071 |
| Chain | Residue | Details |
| N | ARG118 | |
| N | ARG152 | |
| N | GLU276 | |
| N | ARG292 | |
| N | ARG371 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:7994573 |
| Chain | Residue | Details |
| N | ASP293 | |
| N | GLY297 | |
| N | ASP324 | |
| N | ASN347 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:7517697, ECO:0000269|PubMed:7994573 |
| Chain | Residue | Details |
| N | ASN86 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:7994573 |
| Chain | Residue | Details |
| N | ASN146 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04071 |
| Chain | Residue | Details |
| N | ASN200 |
