1LQE
CRYSTAL STRUCTURE OF TRYPSIN IN COMPLEX WITH 79.
Summary for 1LQE
Entry DOI | 10.2210/pdb1lqe/pdb |
Related | 1LPG 1LPK 1LPZ 1LQD |
Descriptor | TRYPSIN, CALCIUM ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | factor xa inhibitor, enzyme-inhibitor complex, blood coagulation factor, serine proteinase, hydrolase |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 26127.54 |
Authors | Schreuder, H.A.,Liesum, A. (deposition date: 2002-05-10, release date: 2003-05-10, Last modification date: 2011-07-13) |
Primary citation | Matter, H.,Defossa, E.,Heinelt, U.,Blohm, P.M.,Schneider, D.,Mueller, A.,Herok, S.,Schreuder, H.A.,Liesum, A.,Brachvogel, V.,Loenze, P.,Walser, A.,Al-Obeidi, F.,Wildgoose, P. Design and quantitative structure-activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa. J.Med.Chem., 45:2749-2769, 2002 Cited by PubMed: 12061878DOI: 10.1021/jm0111346 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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