1IR3

PHOSPHORYLATED INSULIN RECEPTOR TYROSINE KINASE IN COMPLEX WITH PEPTIDE SUBSTRATE AND ATP ANALOG

1IR3 の概要

• エントリーDOI: 10.2210/pdb1ir3/pdb
• 分子名称: INSULIN RECEPTOR, PEPTIDE SUBSTRATE, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: tyrosine kinase, signal transduction, phosphotransferase, complex (kinase-peptide substrate-atp analog), enzyme, complex (transferase-substrate), complex (transferase-substrate) complex, complex (transferase/substrate)
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P06213
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37542.82

構造登録者

Hubbard, S.R. (登録日: 1997-09-22, 公開日: 1998-01-07, 最終更新日: 2023-08-09)

• 主引用文献: Hubbard, S.R.; Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog.; EMBO J., 16:5572-5581, 1997; PubMed: 9312016; DOI: 10.1093/emboj/16.18.5572

実験手法

X-RAY DIFFRACTION (1.9 Å)