1IR3
PHOSPHORYLATED INSULIN RECEPTOR TYROSINE KINASE IN COMPLEX WITH PEPTIDE SUBSTRATE AND ATP ANALOG
Summary for 1IR3
Entry DOI | 10.2210/pdb1ir3/pdb |
Descriptor | INSULIN RECEPTOR, PEPTIDE SUBSTRATE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | tyrosine kinase, signal transduction, phosphotransferase, complex (kinase-peptide substrate-atp analog), enzyme, complex (transferase-substrate), complex (transferase-substrate) complex, complex (transferase/substrate) |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: P06213 |
Total number of polymer chains | 2 |
Total formula weight | 37542.82 |
Authors | Hubbard, S.R. (deposition date: 1997-09-22, release date: 1998-01-07, Last modification date: 2023-08-09) |
Primary citation | Hubbard, S.R. Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog. EMBO J., 16:5572-5581, 1997 Cited by PubMed: 9312016DOI: 10.1093/emboj/16.18.5572 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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