1BGX

TAQ POLYMERASE IN COMPLEX WITH TP7, AN INHIBITORY FAB

1BGX の概要

• エントリーDOI: 10.2210/pdb1bgx/pdb
• 分子名称: TAQ DNA POLYMERASE, TP7 MAB, ... (4 entities in total)
• 機能のキーワード: dna polymerase, fab, pcr, inhibition, helix-coil dynamics, inhibitor design, complex (polymerase-inhibitor), complex (polymerase-inhibitor) complex, complex (polymerase/inhibitor)
• 由来する生物種: Thermus aquaticus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 140719.07

構造登録者

Murali, R.,Sharkey, D.J.,Daiss, J.L.,Krishna Murthy, H.M. (登録日: 1998-06-02, 公開日: 1998-10-14, 最終更新日: 2023-08-02)

• 主引用文献: Murali, R.,Sharkey, D.J.,Daiss, J.L.,Murthy, H.M.; Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme.; Proc.Natl.Acad.Sci.USA, 95:12562-12567, 1998; PubMed: 9770525; DOI: 10.1073/pnas.95.21.12562

実験手法

X-RAY DIFFRACTION (2.3 Å)