1BGX
TAQ POLYMERASE IN COMPLEX WITH TP7, AN INHIBITORY FAB
Summary for 1BGX
| Entry DOI | 10.2210/pdb1bgx/pdb |
| Descriptor | TAQ DNA POLYMERASE, TP7 MAB, ... (4 entities in total) |
| Functional Keywords | dna polymerase, fab, pcr, inhibition, helix-coil dynamics, inhibitor design, complex (polymerase-inhibitor), complex (polymerase-inhibitor) complex, complex (polymerase/inhibitor) |
| Biological source | Thermus aquaticus More |
| Total number of polymer chains | 3 |
| Total formula weight | 140719.07 |
| Authors | Murali, R.,Sharkey, D.J.,Daiss, J.L.,Krishna Murthy, H.M. (deposition date: 1998-06-02, release date: 1998-10-14, Last modification date: 2023-08-02) |
| Primary citation | Murali, R.,Sharkey, D.J.,Daiss, J.L.,Murthy, H.M. Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme. Proc.Natl.Acad.Sci.USA, 95:12562-12567, 1998 Cited by PubMed: 9770525DOI: 10.1073/pnas.95.21.12562 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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