8ALY
Cryo-EM structure of human tankyrase 2 SAM-PARP filament (G1032W mutant)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | E, J, I, H, G... | Poly [ADP-ribose] polymerase tankyrase-2 | polymer | 299 | 34077.7 | 20 | UniProt (Q9H2K2) Pfam (PF07647) Pfam (PF00644) In PDB | Homo sapiens (human) | ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein |
| 2 | D, C, B, A, O... | ZINC ION | non-polymer | 65.4 | 20 | Chemie (ZN) |
Sequence modifications
E, J, I, H, G, F, D, C, B, A, O, T, S, R, Q, P, N, M, L, K: 867 - 1162 (UniProt: Q9H2K2)
| PDB | External Database | Details |
|---|---|---|
| Ser 864 | - | expression tag |
| Asn 865 | - | expression tag |
| Ala 866 | - | expression tag |
| Trp 1032 | Gly 1032 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 681553.4 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1308.2 | |
| All* | Total formula weight | 682861.5 |
