8ALY

Cryo-EM structure of human tankyrase 2 SAM-PARP filament (G1032W mutant)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
B	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
C	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
D	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
E	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
F	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
G	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
H	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
I	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
J	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
K	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
L	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
M	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
N	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
O	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
P	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
Q	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
R	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
S	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
T	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	BINDING: BINDING => ECO:0000250|UniProtKB:O95271

Chain	Residue	Details
E	CYS1081
I	HIS1084
I	CYS1089
I	CYS1092
H	CYS1081
H	HIS1084
H	CYS1089
H	CYS1092
G	CYS1081
G	HIS1084
G	CYS1089
E	HIS1084
G	CYS1092
F	CYS1081
F	HIS1084
F	CYS1089
F	CYS1092
D	CYS1081
D	HIS1084
D	CYS1089
D	CYS1092
C	CYS1081
E	CYS1089
C	HIS1084
C	CYS1089
C	CYS1092
B	CYS1081
B	HIS1084
B	CYS1089
B	CYS1092
A	CYS1081
A	HIS1084
A	CYS1089
E	CYS1092
A	CYS1092
O	CYS1081
O	HIS1084
O	CYS1089
O	CYS1092
T	CYS1081
T	HIS1084
T	CYS1089
T	CYS1092
S	CYS1081
J	CYS1081
S	HIS1084
S	CYS1089
S	CYS1092
R	CYS1081
R	HIS1084
R	CYS1089
R	CYS1092
Q	CYS1081
Q	HIS1084
Q	CYS1089
J	HIS1084
Q	CYS1092
P	CYS1081
P	HIS1084
P	CYS1089
P	CYS1092
N	CYS1081
N	HIS1084
N	CYS1089
N	CYS1092
M	CYS1081
J	CYS1089
M	HIS1084
M	CYS1089
M	CYS1092
L	CYS1081
L	HIS1084
L	CYS1089
L	CYS1092
K	CYS1081
K	HIS1084
K	CYS1089
J	CYS1092
K	CYS1092
I	CYS1081

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