7UAH
Macrocyclic plasmin inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Plasminogen | polymer | 250 | 27319.4 | 2 | UniProt (P00747) Pfam (PF00089) In PDB | Homo sapiens (human) | |
| 2 | A, B | (6S,9R,19S,22R)-N-{[4-(aminomethyl)phenyl]methyl}-22-[(3-chlorobenzene-1-sulfonyl)amino]-3,12,21-trioxo-2,6,9,13,20-pentaazatetracyclo[22.2.2.2~6,9~.2~14,17~]dotriaconta-1(26),14,16,24,27,29-hexaene-19-carboxamide | non-polymer | 829.4 | 2 | Chemie (M63) | |||
| 3 | A, B | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | B | (2~{R})-butane-1,2-diol | non-polymer | 90.1 | 1 | Chemie (NZ5) | |||
| 5 | water | water | 18.0 | 370 | Chemie (HOH) |
Sequence modifications
A, B: 542 - 791 (UniProt: P00747)
| PDB | External Database | Details |
|---|---|---|
| Ala 741 | Ser 760 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54638.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2037.1 | |
| All* | Total formula weight | 56675.9 |
