5HZK
Crystal structure of photoinhibitable Intersectin1 containing wildtype LOV2 domain in complex with Cdc42
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Cell division control protein 42 homolog | polymer | 190 | 21083.2 | 2 | UniProt (P60953) UniProt (by SIFTS) (P60953-1) In PDB | Homo sapiens (Human) | G25K GTP-binding protein |
2 | B, D | Intersectin-1,NPH1-1,Intersectin-1 | polymer | 502 | 58281.1 | 2 | UniProt (Q15811) UniProt (O49003) Pfam (PF00621) Pfam (PF13426) Pfam (PF16652) In PDB | Homo sapiens (Human) | SH3 domain-containing protein 1A,SH3P17,SH3 domain-containing protein 1A,SH3P17 |
3 | A, C | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
4 | B, D | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 2 | Chemie (FMN) |
Sequence modifications
A, C: 1 - 188 (UniProt: P60953)
B, D: 1230 - 1308 (UniProt: Q15811)
B, D: 1309 - 1451 (UniProt: O49003)
B, D: 1452 - 1723 (UniProt: Q15811)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ala 0 | - | expression tag |
Ser 188 | Cys 188 | engineered mutation |
B, D: 1309 - 1451 (UniProt: O49003)
B, D: 1452 - 1723 (UniProt: Q15811)
PDB | External Database | Details |
---|---|---|
Leu 1724 | - | expression tag |
Glu 1725 | - | expression tag |
His 1726 | - | expression tag |
His 1727 | - | expression tag |
His 1728 | - | expression tag |
His 1729 | - | expression tag |
His 1730 | - | expression tag |
His 1731 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 158728.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1799.1 | |
All* | Total formula weight | 160527.7 |