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5HZK

Crystal structure of photoinhibitable Intersectin1 containing wildtype LOV2 domain in complex with Cdc42

Summary for 5HZK
Entry DOI10.2210/pdb5hzk/pdb
DescriptorCell division control protein 42 homolog, Intersectin-1,NPH1-1,Intersectin-1, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywordssignaling protein, photoswitch, chimera, complex
Biological sourceHomo sapiens (Human)
More
Cellular locationCell membrane ; Lipid-anchor ; Cytoplasmic side : P60953
Endomembrane system : Q15811
Total number of polymer chains4
Total formula weight160527.68
Authors
Tarnawski, M.,Dagliyan, O.,Chu, P.H.,Shirvanyants, D.,Dokholyan, N.V.,Hahn, K.M.,Schlichting, I. (deposition date: 2016-02-02, release date: 2016-12-21, Last modification date: 2024-01-10)
Primary citationDagliyan, O.,Tarnawski, M.,Chu, P.H.,Shirvanyants, D.,Schlichting, I.,Dokholyan, N.V.,Hahn, K.M.
Engineering extrinsic disorder to control protein activity in living cells.
Science, 354:1441-1444, 2016
Cited by
PubMed: 27980211
DOI: 10.1126/science.aah3404
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.3 Å)
Structure validation

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