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4WN5

Crystal structure of the C-terminal Per-Arnt-Sim (PASb) of human HIF-3alpha9 bound to 18:1-1-monoacylglycerol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BHypoxia-inducible factor 3-alphapolymer11512521.02UniProt (Q9Y2N7)
Pfam (PF14598)
In PDB
Homo sapiens (Human)HIF3-alpha,Basic-helix-loop-helix-PAS protein MOP7,Class E basic helix-loop-helix protein 17,bHLHe17,HIF3-alpha-1,Inhibitory PAS domain protein,IPAS,Member of PAS protein 7,PAS domain-containing protein 7
2A, BSULFATE IONnon-polymer96.12Chemie (SO4)
3A, BMONOVACCENINnon-polymer356.52Chemie (MVC)
4A, BHEXAETHYLENE GLYCOLnon-polymer282.35Chemie (P6G)
5waterwater18.0295Chemie (HOH)
Sequence modifications
A, B: 237 - 347 (UniProt: Q9Y2N7)
PDBExternal DatabaseDetails
Gly 233-expression tag
Ser 234-expression tag
His 235-expression tag
Met 236-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight25041.9
Non-Polymers*Number of molecules9
Total formula weight2316.9
All*Total formula weight27358.8
*Water molecules are not included.

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PDB entries from 2024-05-01

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