4WN5
Crystal structure of the C-terminal Per-Arnt-Sim (PASb) of human HIF-3alpha9 bound to 18:1-1-monoacylglycerol
Summary for 4WN5
Entry DOI | 10.2210/pdb4wn5/pdb |
Descriptor | Hypoxia-inducible factor 3-alpha, SULFATE ION, MONOVACCENIN, ... (5 entities in total) |
Functional Keywords | hif-3alpha, pas domain, monoacylglycerol, lipid, fatty acid, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 27358.77 |
Authors | Fala, A.M.,Oliveira, J.F.,Dias, S.M.,Ambrosio, A.L. (deposition date: 2014-10-10, release date: 2015-08-05, Last modification date: 2023-09-27) |
Primary citation | Fala, A.M.,Oliveira, J.F.,Adamoski, D.,Aricetti, J.A.,Dias, M.M.,Dias, M.V.B.,Sforca, M.L.,Lopes-de-Oliveira, P.S.,Rocco, S.A.,Caldana, C.,Dias, S.M.G.,Ambrosio, A.L.B. Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3 alpha. Sci Rep, 5:12698-12698, 2015 Cited by PubMed: 26237540DOI: 10.1038/srep12698 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.15 Å) |
Structure validation
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