4QI9
Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Dihydrofolate reductase | polymer | 167 | 19258.6 | 3 | UniProt (Q7CG83) Pfam (PF00186) UniProt (by SIFTS) (A0A3N4BLI0) In PDB | Yersinia pestis | |
2 | A, B, C | METHOTREXATE | non-polymer | 454.4 | 3 | Chemie (MTX) | |||
3 | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 160 (UniProt: Q7CG83)
PDB | External Database | Details |
---|---|---|
Gly 161 | - | expression tag |
Glu 162 | - | expression tag |
Asn 163 | - | expression tag |
Leu 164 | - | expression tag |
Tyr 165 | - | expression tag |
Phe 166 | - | expression tag |
Gln 167 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 57775.7 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1363.3 | |
All* | Total formula weight | 59139.0 |