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4QI9

Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate

Summary for 4QI9
Entry DOI10.2210/pdb4qi9/pdb
Related3Q1H
DescriptorDihydrofolate reductase, METHOTREXATE (3 entities in total)
Functional Keywordsstructural genomics, center for structural genomics of infectious diseases, csgid, alpha beta fold, niaid, national institute of allergy and infectious diseases, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceYersinia pestis
Total number of polymer chains3
Total formula weight59139.01
Authors
Primary citationMaltseva, N.,Kim, Y.,Makowska-Grzyska, M.,Mulligan, R.,Shatsman, S.,Anderson, W.F.,Joachimiak, A.
Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate
To be Published,
Experimental method
X-RAY DIFFRACTION (2.297 Å)
Structure validation

217705

PDB entries from 2024-03-27

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