4OV6

Crystal structure of PCSK9(53-451) with Adnectin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Proprotein convertase subtilisin/kexin type 9	polymer	93	10591.2	2	UniProt (Q8NBP7) Pfam (PF05922) In PDB	Homo sapiens (human)	PCSK9, Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9
2	B, E	Proprotein convertase subtilisin/kexin type 9	polymer	294	31295.4	2	UniProt (Q8NBP7) Pfam (PF00082) In PDB	Homo sapiens (human)	PCSK9, Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9
3	F, G	Adnectin	polymer	99	10864.0	2	Pfam (PF00041) UniProt (by SIFTS) (A0A075B5G3) In PDB	Homo sapiens (human)
4	A, B, E	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
5	B, D	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
6		water	water		18.0	130	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	105501.2
Non-Polymers*	Number of molecules	7
	Total formula weight	698.8
All*	Total formula weight	106200.0

*Water molecules are not included.