3RN2
Structural Basis of Cytosolic DNA Recognition by Innate Immune Receptors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Interferon-inducible protein AIM2 | polymer | 208 | 23480.5 | 2 | UniProt (O14862) Pfam (PF02760) In PDB | Homo sapiens (human) | Absent in melanoma 2 |
| 2 | K, L | DNA (5'-D(*CP*CP*AP*TP*CP*AP*AP*AP*GP*AP*TP*CP*TP*TP*TP*GP*AP*TP*GP*G)-3') | polymer | 20 | 6133.0 | 2 | |||
| 3 | A, B, L | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A, B: 144 - 343 (UniProt: O14862)
| PDB | External Database | Details |
|---|---|---|
| Gly 140 | - | expression tag |
| Ser 141 | - | expression tag |
| Val 142 | - | expression tag |
| Asp 143 | - | expression tag |
| Ala 344 | - | expression tag |
| Ala 345 | - | expression tag |
| Ala 346 | - | expression tag |
| Ser 347 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 59226.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 372.4 | |
| All* | Total formula weight | 59599.3 |
