3OV1

Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Growth factor receptor-bound protein 2	polymer	117	13758.5	1	UniProt (P62993) Pfam (PF00017) In PDB	Homo sapiens	Adapter protein GRB2, SH2/SH3 adapter GRB2, Protein Ash
2	B	PYAC3CN	polymer	5	497.4	1
3	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	A	FORMIC ACID	non-polymer		46.0	1	Chemie (FMT)
5	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
6		water	water		18.0	108	Chemie (HOH)

Sequence modifications

A: 53 - 163 (UniProt: P62993)

PDB	External Database	Details
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	14255.9
Non-Polymers*	Number of molecules	4
	Total formula weight	253.2
All*	Total formula weight	14509.1

*Water molecules are not included.