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2Z5Y

Crystal Structure of Human Monoamine Oxidase A (G110A) with Harmine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AAmine oxidase [flavin-containing] Apolymer51358271.91UniProt (P21397)
Pfam (PF01593)
In PDB
Homo sapiens (human)Monoamine oxidase type A, MAO-A
2AFLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.51Chemie (FAD)
3A7-METHOXY-1-METHYL-9H-BETA-CARBOLINEnon-polymer212.21Chemie (HRM)
4ADECYL(DIMETHYL)PHOSPHINE OXIDEnon-polymer218.32Chemie (DCX)
5waterwater18.0199Chemie (HOH)
Sequence modifications
A: 12 - 524 (UniProt: P21397)
PDBExternal DatabaseDetails
Ala 110Gly 110engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight58271.9
Non-Polymers*Number of molecules4
Total formula weight1434.4
All*Total formula weight59706.3
*Water molecules are not included.

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PDB entries from 2024-04-24

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