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2Z5Y

Crystal Structure of Human Monoamine Oxidase A (G110A) with Harmine

Summary for 2Z5Y
Entry DOI10.2210/pdb2z5y/pdb
Related2Z5X
DescriptorAmine oxidase [flavin-containing] A, FLAVIN-ADENINE DINUCLEOTIDE, 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE, ... (5 entities in total)
Functional Keywordshuman monoamine oxidase a, mutant, g110a, fad, harmine, dimethyldecylphosphine oxide, single helix trans-membrane protein, acetylation, catecholamine metabolism, flavoprotein, mitochondrion, neurotransmitter degradation, oxidoreductase, polymorphism, transmembrane
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side: P21397
Total number of polymer chains1
Total formula weight59706.30
Authors
Son, S.Y.,Ma, J.,Yoshimura, M.,Tsukihara, T. (deposition date: 2007-07-20, release date: 2008-04-01, Last modification date: 2023-11-01)
Primary citationSon, S.Y.,Ma, J.,Kondou, Y.,Yoshimura, M.,Yamashita, E.,Tsukihara, T.
Structure of human monoamine oxidase A at 2.2-A resolution: The control of opening the entry for substrates/inhibitors
Proc.Natl.Acad.Sci.Usa, 105:5739-5744, 2008
Cited by
PubMed: 18391214
DOI: 10.1073/pnas.0710626105
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.17 Å)
Structure validation

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