1YHM

Structure of the complex of Trypanosoma cruzi farnesyl disphosphate synthase with alendronate, Isopentenyl diphosphate and mg+2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	farnesyl pyrophosphate synthase	polymer	362	41928.7	3	UniProt (Q8WS26) Pfam (PF00348) In PDB	Trypanosoma cruzi
2	A, B, C	MAGNESIUM ION	non-polymer		24.3	9	Chemie (MG)
3	A, B, C	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	A, B, C	4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE	non-polymer		245.1	3	Chemie (AHD)
5	A, B, C	3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE	non-polymer		246.1	3	Chemie (IPE)
6		water	water		18.0	110	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 362 (UniProt: Q8WS26)

PDB	External Database	Details
Mse 4	Met 4	modified residue
Mse 39	Met 39	modified residue
Mse 40	Met 40	modified residue
Mse 53	Met 53	modified residue
Mse 86	Met 86	modified residue
Mse 101	Met 101	modified residue
Mse 106	Met 106	modified residue
Mse 138	Met 138	modified residue
Mse 168	Met 168	modified residue
Mse 174	Met 174	modified residue
Mse 188	Met 188	modified residue
Mse 219	Met 219	modified residue
Mse 232	Met 232	modified residue
Mse 253	Met 253	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	125786.2
Non-Polymers*	Number of molecules	18
	Total formula weight	1980.4
All*	Total formula weight	127766.6

*Water molecules are not included.