1YHM
Structure of the complex of Trypanosoma cruzi farnesyl disphosphate synthase with alendronate, Isopentenyl diphosphate and mg+2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | farnesyl pyrophosphate synthase | polymer | 362 | 41928.7 | 3 | UniProt (Q8WS26) Pfam (PF00348) In PDB | Trypanosoma cruzi | |
2 | A, B, C | MAGNESIUM ION | non-polymer | 24.3 | 9 | Chemie (MG) | |||
3 | A, B, C | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
4 | A, B, C | 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE | non-polymer | 245.1 | 3 | Chemie (AHD) | |||
5 | A, B, C | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE | non-polymer | 246.1 | 3 | Chemie (IPE) | |||
6 | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 362 (UniProt: Q8WS26)
PDB | External Database | Details |
---|---|---|
Mse 4 | Met 4 | modified residue |
Mse 39 | Met 39 | modified residue |
Mse 40 | Met 40 | modified residue |
Mse 53 | Met 53 | modified residue |
Mse 86 | Met 86 | modified residue |
Mse 101 | Met 101 | modified residue |
Mse 106 | Met 106 | modified residue |
Mse 138 | Met 138 | modified residue |
Mse 168 | Met 168 | modified residue |
Mse 174 | Met 174 | modified residue |
Mse 188 | Met 188 | modified residue |
Mse 219 | Met 219 | modified residue |
Mse 232 | Met 232 | modified residue |
Mse 253 | Met 253 | modified residue |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 125786.2 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 1980.4 | |
All* | Total formula weight | 127766.6 |