PDB: 10 resultsInfo pagesStatus searchChemie searchBIRD

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6DZS	Mycobacterial homoserine dehydrogenase ThrA in complex with NADP Descriptor: Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Chaton, C.T, Rodriguez, E.S, Korotkov, K.V. Deposit date: 2018-07-05 Release date: 2018-07-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Structure of mycobacterial homoserine dehydrogenase ThrA To be Published
3JZB	Crystal Structure of TR-alfa bound to the selective thyromimetic TRIAC Descriptor: THRA protein, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID Authors: Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R. Deposit date: 2009-09-23 Release date: 2009-12-08 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.007 Å) Cite: Gaining ligand selectivity in thyroid hormone receptors via entropy. Proc.Natl.Acad.Sci.USA, 106, 2009
2H77	Crystal structure of human TR alpha bound T3 in monoclinic space group Descriptor: 3,5,3'TRIIODOTHYRONINE, THRA protein Authors: Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Bleicher, L, Ambrosio, A.L.B, Figueira, A.C.M, Santos, M.A.M, Neto, M.O, Fischer, H, Togashi, H.F.M, Craievich, A.F, Garrat, R.C, Baxter, J.D, Webb, P, Polikarpov, I. Deposit date: 2006-06-01 Release date: 2006-07-25 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function. J.Mol.Biol., 360, 2006
2H79	Crystal Structure of human TR alpha bound T3 in orthorhombic space group Descriptor: 3,5,3'TRIIODOTHYRONINE, THRA protein Authors: Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Bleicher, L, Ambrosio, A.L.B, Figueira, A.C.M, Santos, M.A.M, Neto, M.O, Fischer, H, Togashi, H.F.M, Craievich, A.F, Garrat, R.C, Baxter, J.D, Webb, P, Polikarpov, I. Deposit date: 2006-06-01 Release date: 2006-07-25 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function. J.Mol.Biol., 360, 2006
7QDT	Crystal structure of a mutant (P393GX) Thyroid Receptor Alpha ligand binding domain designed to model dominant negative human mutations. Descriptor: 3,5,3'TRIIODOTHYRONINE, Isoform Alpha-1 of Thyroid hormone receptor alpha Authors: Romartinez-Alonso, B, Fairall, L, Agostini, M, Chatterjee, K, Schwabe, J. Deposit date: 2021-11-30 Release date: 2022-01-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3 Å) Cite: Structure-Guided Approach to Relieving Transcriptional Repression in Resistance to Thyroid Hormone alpha. Mol.Cell.Biol., 42, 2022
3UVV	Crystal Structure of the ligand binding domains of the thyroid receptor:retinoid X receptor complexed with 3,3',5 triiodo-L-thyronine and 9-cis retinoic acid Descriptor: (9cis)-retinoic acid, 3,5,3'TRIIODOTHYRONINE, Retinoic acid receptor RXR-alpha, ... Authors: Fernandez, E.J, Putcha, B.-D.K, Wright, E, Brunzelle, J.S. Deposit date: 2011-11-30 Release date: 2012-04-18 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structural basis for negative cooperativity within agonist-bound TR:RXR heterodimers. Proc.Natl.Acad.Sci.USA, 109, 2012
6MX1	The crystal structure of the regulatory domain of aspartokinase in the bifunctional aspartokinase/homoserine dehydrogenase 1 from Escherichia coli str. K-12 substr. MG1655 Descriptor: Bifunctional aspartokinase/homoserine dehydrogenase 1 Authors: Tan, K, Endres, M, Welk, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2018-10-30 Release date: 2018-11-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.671 Å) Cite: The crystal structure of the regulatory domain of aspartokinase in the bifunctional aspartokinase/homoserine dehydrogenase 1 from Escherichia coli str. K-12 substr. MG1655 To Be Published
4LNW	Crystal structure of TR-alpha bound to T3 in a second site Descriptor: 3,5,3'TRIIODOTHYRONINE, Thyroid hormone receptor alpha Authors: Puhl, A.C, Aparicio, R, Polikarpov, I. Deposit date: 2013-07-12 Release date: 2014-03-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Identification of a new hormone-binding site on the surface of thyroid hormone receptor. Mol.Endocrinol., 28, 2014
4LNX	Crystal structure of TR-alpha bound to T4 in a second site Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, 3,5,3'TRIIODOTHYRONINE, Thyroid hormone receptor alpha Authors: Puhl, A.C, Aparicio, R, Polikarpov, I. Deposit date: 2013-07-12 Release date: 2014-03-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Identification of a new hormone-binding site on the surface of thyroid hormone receptor. Mol.Endocrinol., 28, 2014
3HZF	Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group Descriptor: Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid Authors: Aparicio, R, Bleicher, L, Polikarpov, I. Deposit date: 2009-06-23 Release date: 2009-07-21 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms. Bmc Struct.Biol., 8, 2008