PDB: 30 resultsInfo pagesStatus searchChemie searchBIRD

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4WFC	Structure of the Rrp6-Rrp47 interaction Descriptor: Exosome complex exonuclease RRP6, Exosome complex protein LRP1, SULFATE ION Authors: Schuch, B, Conti, E. Deposit date: 2014-09-14 Release date: 2014-10-29 Last modified: 2017-09-06 Method: X-RAY DIFFRACTION (2.35 Å) Cite: The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase. Embo J., 33, 2014
4WFD	Structure of the Rrp6-Rrp47-Mtr4 interaction Descriptor: ATP-dependent RNA helicase DOB1, Exosome complex exonuclease RRP6, Exosome complex protein LRP1, ... Authors: Schuch, B, Conti, E. Deposit date: 2014-09-14 Release date: 2014-10-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase. Embo J., 33, 2014
4OO1	Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Exosome complex component CSL4, ... Authors: Lima, C.D, Wasmuth, E.V. Deposit date: 2014-01-29 Release date: 2014-07-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA. Nature, 511, 2014
4NLB	Crystal structure of the catalytic core of RRP6 from Trypanosoma brucei Descriptor: Ribosomal RNA processing protein 6 Authors: Barbosa, R.L, Guimaraes, B.G. Deposit date: 2013-11-14 Release date: 2014-03-26 Method: X-RAY DIFFRACTION (2.4 Å) Cite: RRP6 from Trypanosoma brucei: Crystal Structure of the Catalytic Domain, Association with EAP3 and Activity towards Structured and Non-Structured RNA Substrates Plos One, 9, 2014
4NLC	Crystal structure of the catalytic core of RRP6 from Trypanosoma brucei, mutant C496S Descriptor: DI(HYDROXYETHYL)ETHER, Ribosomal RNA processing protein 6 Authors: Barbosa, R.L, Guimaraes, B.G. Deposit date: 2013-11-14 Release date: 2014-03-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.15 Å) Cite: RRP6 from Trypanosoma brucei: Crystal Structure of the Catalytic Domain, Association with EAP3 and Activity towards Structured and Non-Structured RNA Substrates Plos One, 9, 2014
3SAF	Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site Descriptor: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION Authors: Januszyk, K, Liu, Q, Lima, C.D. Deposit date: 2011-06-02 Release date: 2011-07-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Activities of human RRP6 and structure of the human RRP6 catalytic domain. Rna, 17, 2011
3SAG	Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site Descriptor: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION Authors: Januszyk, K, Liu, Q, Lima, C.D. Deposit date: 2011-06-02 Release date: 2011-07-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Activities of human RRP6 and structure of the human RRP6 catalytic domain. Rna, 17, 2011
3SAH	Crystal structure of the human RRP6 catalytic domain with Y436A mutation in the catalytic site Descriptor: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION Authors: Januszyk, K, Liu, Q, Lima, C.D. Deposit date: 2011-06-02 Release date: 2011-07-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Activities of human RRP6 and structure of the human RRP6 catalytic domain. Rna, 17, 2011
5C0Y	Crystal structure of the Rrp6 catalytic domain bound to poly(U) RNA Descriptor: Exosome complex exonuclease RRP6, MAGNESIUM ION, poly U RNA Authors: Schuch, B, Conti, E. Deposit date: 2015-06-12 Release date: 2015-08-05 Last modified: 2017-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: RNA degradation paths in a 12-subunit nuclear exosome complex. Nature, 524, 2015
4IFD	Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BROMIDE ION, Exosome complex component CSL4, ... Authors: Makino, D.L, Conti, E. Deposit date: 2012-12-14 Release date: 2013-02-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.805 Å) Cite: Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex. Nature, 495, 2013
5VZJ	STRUCTURE OF A TWELVE COMPONENT MPP6-NUCLEAR RNA EXOSOME COMPLEX BOUND TO RNA Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... Authors: Lima, C.D, Wasmuth, E.V. Deposit date: 2017-05-28 Release date: 2017-08-02 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase. Elife, 6, 2017
5K36	Structure of an eleven component nuclear RNA exosome complex bound to RNA Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... Authors: Lima, C.D, Zinder, J.C. Deposit date: 2016-05-19 Release date: 2016-11-02 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Nuclear RNA Exosome at 3.1 angstrom Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3. Mol.Cell, 64, 2016
5C0X	Structure of a 12-subunit nuclear exosome complex bound to structured RNA Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... Authors: Makino, D.L, Conti, E. Deposit date: 2015-06-12 Release date: 2015-08-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.812 Å) Cite: RNA degradation paths in a 12-subunit nuclear exosome complex. Nature, 524, 2015
5C0W	Structure of a 12-subunit nuclear exosome complex bound to single-stranded RNA substrates Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... Authors: Makino, D.L, Conti, E. Deposit date: 2015-06-12 Release date: 2015-07-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (4.6 Å) Cite: RNA degradation paths in a 12-subunit nuclear exosome complex. Nature, 524, 2015
7D4I	Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1 (State F) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... Authors: Du, Y, Zhang, J, An, W, Ye, K. Deposit date: 2020-09-24 Release date: 2021-10-06 Method: ELECTRON MICROSCOPY (4 Å) Cite: Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1 To Be Published
6LQS	Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ... Authors: Du, Y, Ye, K. Deposit date: 2020-01-14 Release date: 2020-09-16 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
6FSZ	Structure of the nuclear RNA exosome Descriptor: ATP-dependent RNA helicase DOB1, Exosome complex component CSL4, Exosome complex component MTR3, ... Authors: Schuller, J.M, Falk, S, Conti, E. Deposit date: 2018-02-20 Release date: 2018-03-21 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018
2HBK	Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain; Protein in complex with Mn Descriptor: Exosome complex exonuclease RRP6, MANGANESE (II) ION Authors: Midtgaard, S.F, Assenholt, J, Jonstrup, A.T, Van, L.B, Jensen, T.H, Brodersen, D.E. Deposit date: 2006-06-14 Release date: 2006-07-25 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HBL	Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain; Protein in complex with Mn, Zn, and AMP Descriptor: ADENOSINE MONOPHOSPHATE, Exosome complex exonuclease RRP6, MANGANESE (II) ION, ... Authors: Midtgaard, S.F, Assenholt, J, Jonstrup, A.T, Van, L.B, Jensen, T.H, Brodersen, D.E. Deposit date: 2006-06-14 Release date: 2006-07-25 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HBJ	Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain Descriptor: Exosome complex exonuclease RRP6 Authors: Midtgaard, S.F, Assenholt, J, Jonstrup, A.T, Van, L.B, Jensen, T.H, Brodersen, D.E. Deposit date: 2006-06-14 Release date: 2006-07-25 Last modified: 2021-11-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HBM	Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain; Protein in complex with Mn, Zn, and UMP Descriptor: Exosome complex exonuclease RRP6, MANGANESE (II) ION, URIDINE-5'-MONOPHOSPHATE, ... Authors: Midtgaard, S.F, Assenholt, J, Jonstrup, A.T, Van, L.B, Jensen, T.H, Brodersen, D.E. Deposit date: 2006-06-14 Release date: 2006-07-25 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain. Proc.Natl.Acad.Sci.Usa, 103, 2006
6FT6	Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors Descriptor: 25S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L11-A, ... Authors: Schuller, J.M, Falk, S, Conti, E. Deposit date: 2018-02-20 Release date: 2018-03-28 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018
5G06	Cryo-EM structure of yeast cytoplasmic exosome Descriptor: EXOSOME COMPLEX COMPONENT CSL4, EXOSOME COMPLEX COMPONENT MTR3, EXOSOME COMPLEX COMPONENT RRP4, ... Authors: Liu, J.J, Niu, C.Y, Wu, Y, Tan, D, Wang, Y, Ye, M.D, Liu, Y, Zhao, W.W, Zhou, K, Liu, Q.S, Dai, J.B, Yang, X.R, Dong, M.Q, Huang, N, Wang, H.W. Deposit date: 2016-03-17 Release date: 2016-06-15 Last modified: 2017-08-02 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Cryoem Structure of Yeast Cytoplasmic Exosome Complex. Cell Res., 26, 2016
7SUK	Structure of Bfr2-Lcp5 Complex Observed in the Small Subunit Processome Isolated from R2TP-depleted Yeast Cells Descriptor: 18S pre-rRNA, 40S ribosomal protein S11-A, 40S ribosomal protein S13, ... Authors: Rai, J, Zhao, Y, Li, H. Deposit date: 2021-11-17 Release date: 2022-07-06 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (3.99 Å) Cite: Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome. Commun Biol, 5, 2022
5OKZ	Crystal Strucrure of the Mpp6 Exosome complex Descriptor: CHLORIDE ION, Exosome complex component CSL4, Exosome complex component MTR3, ... Authors: Falk, S, Ebert, J, Conti, E. Deposit date: 2017-07-26 Release date: 2017-08-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.200039 Å) Cite: Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase. Cell Rep, 20, 2017

 

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