2HBL

Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain; Protein in complex with Mn, Zn, and AMP

Summary for 2HBL

Entry DOI	10.2210/pdb2hbl/pdb
Related	2HBJ 2HBK 2HBM
Descriptor	Exosome complex exonuclease RRP6, ZINC ION, MANGANESE (II) ION, ... (5 entities in total)
Functional Keywords	exosome, rna metabolism, rna surveillance, rna processing, hydrolase, gene regulation
Biological source	Saccharomyces cerevisiae (baker's yeast)
Cellular location	Nucleus, nucleolus : Q12149
Total number of polymer chains	1
Total formula weight	48142.69
Authors	Midtgaard, S.F.,Assenholt, J.,Jonstrup, A.T.,Van, L.B.,Jensen, T.H.,Brodersen, D.E. (deposition date: 2006-06-14, release date: 2006-07-25, Last modification date: 2023-10-25)
Primary citation	Midtgaard, S.F.,Assenholt, J.,Jonstrup, A.T.,Van, L.B.,Jensen, T.H.,Brodersen, D.E. Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain. Proc.Natl.Acad.Sci.Usa, 103:11898-11903, 2006 Cited by PubMed: 16882719 DOI: 10.1073/pnas.0604731103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation