2HBM
Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain; Protein in complex with Mn, Zn, and UMP
Summary for 2HBM
Entry DOI | 10.2210/pdb2hbm/pdb |
Related | 2HBJ 2HBK 2HBL |
Descriptor | Exosome complex exonuclease RRP6, ZINC ION, MANGANESE (II) ION, ... (5 entities in total) |
Functional Keywords | exosome, rna metabolism, rna surveillance, rna processing, hydrolase, gene regulation |
Biological source | Saccharomyces cerevisiae (baker's yeast) |
Cellular location | Nucleus, nucleolus : Q12149 |
Total number of polymer chains | 1 |
Total formula weight | 48119.65 |
Authors | Midtgaard, S.F.,Assenholt, J.,Jonstrup, A.T.,Van, L.B.,Jensen, T.H.,Brodersen, D.E. (deposition date: 2006-06-14, release date: 2006-07-25, Last modification date: 2024-05-29) |
Primary citation | Midtgaard, S.F.,Assenholt, J.,Jonstrup, A.T.,Van, L.B.,Jensen, T.H.,Brodersen, D.E. Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain. Proc.Natl.Acad.Sci.Usa, 103:11898-11903, 2006 Cited by PubMed: 16882719DOI: 10.1073/pnas.0604731103 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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