PDB: 21 resultsInfo pagesStatus searchChemie searchBIRD

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2JA9	Structure of the N-terminal deletion of yeast exosome component Rrp40 Descriptor: EXOSOME COMPLEX EXONUCLEASE RRP40 Authors: Oddone, A, Lorentzen, E, Basquin, J, Gasch, A, Rybin, V, Conti, E, Sattler, M. Deposit date: 2006-11-24 Release date: 2006-12-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural and Biochemical Characterization of the Yeast Exosome Component Rrp40 Embo Rep., 8, 2007
5OKZ	Crystal Strucrure of the Mpp6 Exosome complex Descriptor: CHLORIDE ION, Exosome complex component CSL4, Exosome complex component MTR3, ... Authors: Falk, S, Ebert, J, Conti, E. Deposit date: 2017-07-26 Release date: 2017-08-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.200039 Å) Cite: Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase. Cell Rep, 20, 2017
4OO1	Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Exosome complex component CSL4, ... Authors: Lima, C.D, Wasmuth, E.V. Deposit date: 2014-01-29 Release date: 2014-07-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA. Nature, 511, 2014
5VZJ	STRUCTURE OF A TWELVE COMPONENT MPP6-NUCLEAR RNA EXOSOME COMPLEX BOUND TO RNA Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... Authors: Lima, C.D, Wasmuth, E.V. Deposit date: 2017-05-28 Release date: 2017-08-02 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase. Elife, 6, 2017
5C0X	Structure of a 12-subunit nuclear exosome complex bound to structured RNA Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... Authors: Makino, D.L, Conti, E. Deposit date: 2015-06-12 Release date: 2015-08-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.812 Å) Cite: RNA degradation paths in a 12-subunit nuclear exosome complex. Nature, 524, 2015
4IFD	Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BROMIDE ION, Exosome complex component CSL4, ... Authors: Makino, D.L, Conti, E. Deposit date: 2012-12-14 Release date: 2013-02-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.805 Å) Cite: Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex. Nature, 495, 2013
2NN6	Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4, and Rrp40 Descriptor: 3'-5' exoribonuclease CSL4 homolog, Exosome complex exonuclease RRP4, Exosome complex exonuclease RRP40, ... Authors: Lima, C.D. Deposit date: 2006-10-23 Release date: 2006-12-26 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.35 Å) Cite: Reconstitution, activities, and structure of the eukaryotic RNA exosome. Cell(Cambridge,Mass.), 127, 2006
7D4I	Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1 (State F) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... Authors: Du, Y, Zhang, J, An, W, Ye, K. Deposit date: 2020-09-24 Release date: 2021-10-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (4 Å) Cite: Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1 To Be Published
6LQS	Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ... Authors: Du, Y, Ye, K. Deposit date: 2020-01-14 Release date: 2020-09-16 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
7AJT	Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... Authors: Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E. Deposit date: 2020-09-29 Release date: 2020-12-30 Last modified: 2021-02-03 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome. Mol.Cell, 81, 2021
5C0W	Structure of a 12-subunit nuclear exosome complex bound to single-stranded RNA substrates Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... Authors: Makino, D.L, Conti, E. Deposit date: 2015-06-12 Release date: 2015-07-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (4.6 Å) Cite: RNA degradation paths in a 12-subunit nuclear exosome complex. Nature, 524, 2015
6FSZ	Structure of the nuclear RNA exosome Descriptor: ATP-dependent RNA helicase DOB1, Exosome complex component CSL4, Exosome complex component MTR3, ... Authors: Schuller, J.M, Falk, S, Conti, E. Deposit date: 2018-02-20 Release date: 2018-03-21 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018
5JEA	Structure of a cytoplasmic 11-subunit RNA exosome complex including Ski7, bound to RNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Exosome complex component CSL4, Exosome complex component MTR3, ... Authors: Kowalinski, E, Ebert, J, Stegmann, E, Conti, E. Deposit date: 2016-04-18 Release date: 2016-07-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure of a Cytoplasmic 11-Subunit RNA Exosome Complex. Mol.Cell, 63, 2016
5K36	Structure of an eleven component nuclear RNA exosome complex bound to RNA Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... Authors: Lima, C.D, Zinder, J.C. Deposit date: 2016-05-19 Release date: 2016-11-02 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Nuclear RNA Exosome at 3.1 angstrom Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3. Mol.Cell, 64, 2016
8QCF	yeast cytoplasmic exosome-Ski2 complex degrading a RNA substrate Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Antiviral helicase SKI2, Exosome complex component CSL4, ... Authors: Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. Deposit date: 2023-08-25 Release date: 2024-01-10 Method: ELECTRON MICROSCOPY (2.55 Å) Cite: Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly. Mol.Cell, 83, 2023
5G06	Cryo-EM structure of yeast cytoplasmic exosome Descriptor: EXOSOME COMPLEX COMPONENT CSL4, EXOSOME COMPLEX COMPONENT MTR3, EXOSOME COMPLEX COMPONENT RRP4, ... Authors: Liu, J.J, Niu, C.Y, Wu, Y, Tan, D, Wang, Y, Ye, M.D, Liu, Y, Zhao, W.W, Zhou, K, Liu, Q.S, Dai, J.B, Yang, X.R, Dong, M.Q, Huang, N, Wang, H.W. Deposit date: 2016-03-17 Release date: 2016-06-15 Last modified: 2017-08-02 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Cryoem Structure of Yeast Cytoplasmic Exosome Complex. Cell Res., 26, 2016
7AJU	Cryo-EM structure of the 90S-exosome super-complex (state Post-A1-exosome) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... Authors: Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E. Deposit date: 2020-09-29 Release date: 2020-12-30 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome. Mol.Cell, 81, 2021
6D6R	Human nuclear exosome-MTR4 RNA complex - composite map after focused reconstruction Descriptor: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ... Authors: Weick, E.-M, Lima, C.D. Deposit date: 2018-04-22 Release date: 2018-06-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex. Cell, 173, 2018
6D6Q	Human nuclear exosome-MTR4 RNA complex - overall reconstruction Descriptor: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ... Authors: Weick, E.-M, Lima, C.D. Deposit date: 2018-04-22 Release date: 2018-06-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex. Cell, 173, 2018
6H25	Human nuclear RNA exosome EXO-10-MPP6 complex Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... Authors: Gerlach, P, Schuller, J.M, Falk, S, Basquin, J, Conti, E. Deposit date: 2018-07-13 Release date: 2018-08-15 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Distinct and evolutionary conserved structural features of the human nuclear exosome complex. Elife, 7, 2018
8PEL	Structure of C. thermophilum RNA exosome core Descriptor: Exoribonuclease phosphorolytic domain-containing protein, Exoribonuclease-like protein, Exosome complex component MTR3, ... Authors: Lazzaretti, D, Holdermann, I, Sprangers, R. Deposit date: 2023-06-14 Release date: 2024-06-26 Method: X-RAY DIFFRACTION (3.81 Å) Cite: Beyond static structures: quantitative dynamics in the eukaryotic RNA exosome complex Biorxiv, 2024