8QCF

yeast cytoplasmic exosome-Ski2 complex degrading a RNA substrate

Summary for 8QCF

Entry DOI	10.2210/pdb8qcf/pdb
EMDB information	18329
Descriptor	Exosome complex component RRP45, Exosome complex exonuclease DIS3, Superkiller protein 7, ... (14 entities in total)
Functional Keywords	helicase, rna binding, rna degradation, hydrolase
Biological source	Saccharomyces cerevisiae (brewer's yeast) More
Total number of polymer chains	13
Total formula weight	581981.11
Authors	Keidel, A.,Koegel, A.,Reichelt, P.,Kowalinski, E.,Schaefer, I.B.,Conti, E. (deposition date: 2023-08-25, release date: 2024-01-10)
Primary citation	Keidel, A.,Kogel, A.,Reichelt, P.,Kowalinski, E.,Schafer, I.B.,Conti, E. Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly. Mol.Cell, 83:4093-4105.e7, 2023 Cited by PubMed: 37879335 DOI: 10.1016/j.molcel.2023.09.037 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.55 Å)

Structure validation