1AKO
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EXONUCLEASE III FROM ESCHERICHIA COLI
Descriptor:EXONUCLEASE III
Authors:Mol, C.D., Kuo, C.-F., Thayer, M.M., Cunningham, R.P., Tainer, J.A.
Deposit date:1997-05-26
Release date:1997-08-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and function of the multifunctional DNA-repair enzyme exonuclease III.
Nature, 374, 1995
1BIX
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THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES
Descriptor:AP ENDONUCLEASE 1
Authors:Gorman, M.A., Morera, S., Rothwell, D.G., De La Fortelle, E., Mol, C.D., Tainer, J.A., Hickson, I.D., Freemont, P.S.
Deposit date:1998-06-19
Release date:1999-06-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites.
EMBO J., 16, 1997
1DE8
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HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1) BOUND TO ABASIC DNA
Descriptor:MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE (E.C.4.2.99.18)/DNA COMPLEX
Authors:Mol, C.D., Izumi, T., Mitra, S., Tainer, J.A.
Deposit date:1999-11-13
Release date:2000-02-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected
Nature, 403, 2000
1DE9
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HUMAN APE1 ENDONUCLEASE WITH BOUND ABASIC DNA AND MN2+ ION
Descriptor:MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE (E.C.4.2.99.18)/DNA COMPLEX
Authors:Mol, C.D., Izumi, T., Mitra, S., Tainer, J.A.
Deposit date:1999-11-13
Release date:2000-02-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination
Nature, 403, 2000
1DEW
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CRYSTAL STRUCTURE OF HUMAN APE1 BOUND TO ABASIC DNA
Descriptor:MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE (E.C.4.2.99.18)/DNA COMPLEX
Authors:Mol, C.D., Izumi, T., Mitra, S., Tainer, J.A.
Deposit date:1999-11-15
Release date:2000-02-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination
Nature, 403, 2000
1DNK
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THE X-RAY STRUCTURE OF THE DNASE I-D(GGTATACC)2 COMPLEX AT 2.3 ANGSTROMS RESOLUTION
Descriptor:DEOXYRIBONUCLEASE I (DNASE I) (E.C.3.1.21.1)/DNA COMPLEX + N-ACETYL-D- GLUCOSAMINE
Authors:Weston, S.A., Lahm, A., Suck, D.
Deposit date:1992-08-10
Release date:1994-01-31
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray structure of the DNase I-d(GGTATACC)2 complex at 2.3 A resolution.
J.Mol.Biol., 226, 1992
1E9N
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A SECOND DIVALENT METAL ION IN THE ACTIVE SITE OF A NEW CRYSTAL FORM OF HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE, APE1, AND ITS IMPLICATIONS FOR THE CATALYTIC MECHANISM
Descriptor:DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE (E.C.4.2.99.18)
Authors:Beernink, P.T., Segelke, B.W., Rupp, B.
Deposit date:2000-10-24
Release date:2001-02-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism
J.Mol.Biol., 307, 2001
1HD7
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A SECOND DIVALENT METAL ION IN THE ACTIVE SITE OF A NEW CRYSTAL FORM OF HUMAN APURINIC/APYRIDINIMIC ENDONUCLEASE, APE1, AND ITS IMPLICATIONS FOR THE CATALYTIC MECHANISM
Descriptor:DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE (E.C.4.2.99.18)
Authors:Beernink, P.T., Segelke, B.W., Rupp, B.
Deposit date:2000-11-09
Release date:2001-02-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism
J.Mol.Biol., 307, 2001
1I9Y
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CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 5-PHOSPHATASE DOMAIN (IPP5C) OF SPSYNAPTOJANIN
Descriptor:PHOSPHATIDYLINOSITOL PHOSPHATE PHOSPHATASE
Authors:Tsujishita, Y., Guo, S., Stolz, L., York, J.D., Hurley, J.H.
Deposit date:2001-03-21
Release date:2001-05-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase.
Cell(Cambridge,Mass.), 105, 2001
1I9Z
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CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 5-PHOSPHATASE DOMAIN (IPP5C) OF SPSYNAPTOJANIN IN COMPLEX WITH INOSITOL (1,4)-BISPHOSPHATE AND CALCIUM ION
Descriptor:PHOSPHATIDYLINOSITOL PHOSPHATE PHOSPHATASE
Authors:Tsujishita, Y., Guo, S., Stolz, L., York, J.D., Hurley, J.H.
Deposit date:2001-03-21
Release date:2001-05-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase.
Cell(Cambridge,Mass.), 105, 2001
1VYB
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ENDONUCLEASE DOMAIN OF HUMAN LINE1 ORF2P
Descriptor:ORF2 CONTAINS A REVERSE TRANSCRIPTASE DOMAIN
Authors:Weichenrieder, O., Repanas, K., Perrakis, A.
Deposit date:2004-04-25
Release date:2004-06-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Targeting Endonuclease of the Human Line-1 Retrotransposon
Structure, 12, 2004
1ZWX
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CRYSTAL STRUCTURE OF SMCL
Descriptor:sphingomyelinase-c (E.C.3.1.4.12)
Authors:Openshaw, A.E.A., Race, P.R., Monzo, H.J., Vasquez-Boland, J.A., Banfield, M.J.
Deposit date:2005-06-06
Release date:2005-08-16
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of SmcL, a bacterial neutral sphingomyelinase C from Listeria.
J.Biol.Chem., 280, 2005
2DDR
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CRYSTAL STRUCTURE OF SPHINGOMYELINASE FROM BACILLUS CEREUS WITH CALCIUM ION
Descriptor:Sphingomyelin phosphodiesterase (E.C.3.1.4.12)
Authors:Ago, H., Oda, M., Takahashi, M., Tsuge, H., Ochi, S., Katunuma, N., Miyano, M., Sakurai, J., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-02-02
Release date:2006-05-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Basis of the Sphingomyelin Phosphodiesterase Activity in Neutral Sphingomyelinase from Bacillus cereus.
J.Biol.Chem., 281, 2006
2DDS
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CRYSTAL STRUCTURE OF SPHINGOMYELINASE FROM BACILLUS CEREUS WITH COBALT ION
Descriptor:Sphingomyelin phosphodiesterase (E.C.3.1.4.12)
Authors:Ago, H., Oda, M., Takahashi, M., Tsuge, H., Ochi, S., Katunuma, N., Miyano, M., Sakurai, J., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-02-02
Release date:2006-05-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of the Sphingomyelin Phosphodiesterase Activity in Neutral Sphingomyelinase from Bacillus cereus.
J.Biol.Chem., 281, 2006
2DDT
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CRYSTAL STRUCTURE OF SPHINGOMYELINASE FROM BACILLUS CEREUS WITH MAGNESIUM ION
Descriptor:Sphingomyelin phosphodiesterase (E.C.3.1.4.12)
Authors:Ago, H., Oda, M., Tsuge, H., Katunuma, N., Miyano, M., Sakurai, J., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-02-02
Release date:2006-05-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of the sphingomyelin phosphodiesterase activity in neutral sphingomyelinase from Bacillus cereus.
J.Biol.Chem., 281, 2006
2DNJ
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DNASE I-INDUCED DNA CONFORMATION. 2 ANGSTROMS STRUCTURE OF A DNASE I-OCTAMER COMPLEX
Descriptor:DEOXYRIBONUCLEASE I (DNASE I) (E.C.3.1.21.1)/DNA COMPLEX + N-ACETYL-D- GLUCOSAMINE
Authors:Lahm, A., Suck, D.
Deposit date:1986-10-21
Release date:1994-01-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:DNase I-induced DNA conformation. 2 A structure of a DNase I-octamer complex
J.Mol.Biol., 222, 1991
2F1N
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STRUCTURE OF CDTB, THE BIOLOGICALLY ACTIVE SUBUNIT OF CYTOLETHAL DISTENDING TOXIN
Descriptor:Cytolethal distending toxin subunit B
Authors:Hontz, J.S., Yoder, M.D., Dreyfus, L.A.
Deposit date:2005-11-14
Release date:2006-07-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Differences in Crystal and Solution Structures of the Cytolethal Distending Toxin B Subunit: RELEVANCE TO NUCLEAR TRANSLOCATION AND FUNCTIONAL ACTIVATION.
J.Biol.Chem., 281, 2006
2ISI
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CRYSTAL STRUCTURE OF APE1 FROM HOMO SAPIENS IN A NEW CRYSTAL FORM COMPLEXED WITH A LIGAND
Descriptor:DNA-(apurinic or apyrimidinic site) lyase (E.C.4.2.99.18)
Authors:Agarwal, R., Naidu, M.D.
Deposit date:2006-10-17
Release date:2006-10-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Crystal structure of hApe1 in a new crystal form with a bound ligand: implications on catalytic mechanism and its inhibition
To be Published
2J63
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CRYSTAL STRUCTURE OF AP ENDONUCLEASE LMAP FROM LEISHMANIA MAJOR
Descriptor:AP-ENDONUCLEASE (E.C.4.2.99.18)
Authors:Vidal, A.E., Harkiolaki, M., Gallego, C., Castillo-Acosta, V.M., Ruiz-Perez, L.M., Wilson, K.S., Gonzalez-Pacanowska, D.
Deposit date:2006-09-25
Release date:2007-08-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Crystal Structure and DNA Repair Activities of the Ap Endonuclease from Leishmania Major.
J.Mol.Biol., 373, 2007
2JC4
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3'-5' EXONUCLEASE (NEXO) FROM NEISSERIA MENINGITIDIS
Descriptor:EXODEOXYRIBONUCLEASE III (E.C.3.1.11.2)
Authors:Carpenter, E.P., Corbett, A., Thomson, H., Adacha, J., Jensen, K., Bergeron, J., Kasampalidis, I., Exley, R., Winterbotham, M., Tang, C., Baldwin, G., Freemont, P.
Deposit date:2006-12-19
Release date:2007-03-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
Embo J., 26, 2007
2JC5
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APURINIC APYRIMIDINIC (AP) ENDONUCLEASE (NAPE) FROM NEISSERIA MENINGITIDIS
Descriptor:EXODEOXYRIBONUCLEASE (E.C.3.1.11.2)
Authors:Carpenter, E.P., Corbett, A., Thomson, H., Adacha, J., Jensen, K., Bergeron, J., Kasampalidis, I., Exley, R., Winterbotham, M., Tang, C., Baldwin, G.S., Freemont, P.
Deposit date:2006-12-19
Release date:2007-03-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
Embo J., 26, 2007
2MYI
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SOLUTION STRUCTURE OF CRC FROM P. SYRINGAE LZ4W
Descriptor:Exodeoxyribonuclease III
Authors:Deshmukh, M.V., Sharma, R.
Deposit date:2015-01-25
Release date:2016-01-27
Method:SOLUTION NMR
Cite:Crc binds RNA independent of Hfq
To be Published
2O3C
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CRYSTAL STRUCTURE OF ZEBRAFISH APE
Descriptor:C65 revisited as a critical residue for the redox function of HAPE1
Authors:Georgiadis, M.M., Gaur, R.K., Delaplane, S., Svenson, J.
Deposit date:2006-12-01
Release date:2007-12-11
Modification date:2009-06-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
Mutat.Res., 643, 2008
2O3H
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CRYSTAL STRUCTURE OF THE HUMAN C65A APE
Descriptor:DNA-(apurinic or apyrimidinic site) lyase (E.C.4.2.99.18)
Authors:Georgiadis, M.M., Gaur, R.K., Delaplane, S., Svenson, J.
Deposit date:2006-12-01
Release date:2007-12-11
Modification date:2009-06-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
Mutat.Res., 643, 2008
2UYR
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CRYSTAL STRUCTURE OF BACILLUS CEREUS SPHINGOMYELINASE MUTANT :N57A
Descriptor:SPHINGOMYELINASE C (E.C.3.1.4.12)
Authors:Oda, M., Tsuge, H., Sakurai, J.
Deposit date:2007-04-12
Release date:2008-05-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Bacillus Cereus Sphingomyelinase Mutant : N57A
To be Published
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