6FKE

Structure of 3' phosphatase NExo (D146N) from Neisseria bound to product DNA hairpin

Summary for 6FKE

• Entry DOI: 10.2210/pdb6fke/pdb
• Related: 6FK4 6FK5
• Descriptor: Exodeoxyribonuclease III, DNA (5'-D(*GP*TP*AP*GP*CP*GP*AP*AP*GP*CP*TP*A)-3'), (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
• Functional Keywords: 3' phosphatase, base excision dna repair., dna binding protein
• Biological source: Neisseria meningitidis MC58; More
• Total number of polymer chains: 2
• Total formula weight: 34203.54

Authors

Silhan, J.,Zhao, Q.,Boura, E.,Thomson, H.,Foster, A.,Tang, C.M.,Freemont, P.S.,Baldwin, G.S. (deposition date: 2018-01-23, release date: 2018-10-31, Last modification date: 2024-01-17)

• Primary citation: Silhan, J.,Zhao, Q.,Boura, E.,Thomson, H.,Forster, A.,Tang, C.M.,Freemont, P.S.,Baldwin, G.S.; Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis.; Nucleic Acids Res., 46:11980-11989, 2018; PubMed: 30329088; DOI: 10.1093/nar/gky934

Experimental method

X-RAY DIFFRACTION (2.151 Å)