2V0R

crystal structure of a hairpin exchange variant (LTx) of the targeting LINE-1 retrotransposon endonuclease

Summary for 2V0R

Entry DOI	10.2210/pdb2v0r/pdb
Related	1VYB 2V0S
Descriptor	LTX, SULFATE ION (3 entities in total)
Functional Keywords	ape-1 type, endonuclease, retrotransposition, retrotransposon, protein engineering, transcription
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	2
Total formula weight	55299.38
Authors	Repanas, K.,Zingler, N.,Layer, L.E.,Schumann, G.G.,Perrakis, A.,Weichenrieder, O. (deposition date: 2007-05-17, release date: 2007-07-17, Last modification date: 2023-12-13)
Primary citation	Repanas, K.,Zingler, N.,Layer, L.E.,Schumann, G.G.,Perrakis, A.,Weichenrieder, O. Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease Nucleic Acids Res., 35:4914-, 2007 Cited by PubMed: 17626046 DOI: 10.1093/NAR/GKM516 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation