2V0S

crystal structure of a hairpin exchange variant (LR1) of the targeting LINE-1 retrotransposon endonuclease

Summary for 2V0S

• Entry DOI: 10.2210/pdb2v0s/pdb
• Related: 1VYB 2V0R
• Descriptor: LR1, MANGANESE (II) ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: transcription, ape-1 type, endonuclease, retrotransposition, retrotransposon, protein engineering, hypothetical protein
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 27106.91

Authors

Repanas, K.,Zingler, N.,Layer, L.E.,Schumann, G.G.,Perrakis, A.,Weichenrieder, O. (deposition date: 2007-05-17, release date: 2007-07-17, Last modification date: 2023-12-13)

• Primary citation: Repanas, K.,Zingler, N.,Layer, L.E.,Schumann, G.G.,Perrakis, A.,Weichenrieder, O.; Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease.; Nucleic Acids Res., 35:4914-, 2007; PubMed: 17626046; DOI: 10.1093/NAR/GKM516

Experimental method

X-RAY DIFFRACTION (1.8 Å)