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1KHB
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1khb
PEPCK COMPLEX WITH NONHYDROLYZABLE GTP ANALOG, NATIVE DATA
Descriptor:Phosphoenolpyruvate carboxykinase (E.C.4.1.1.32)
Authors:Dunten, P., Belunis, C., Crowther, R., Hollfelder, K., Kammlott, U., Levin, W., Michel, H., Ramsey, G.B., Swain, A., Weber, D., Wertheimer, S.J.
Deposit date:2001-11-29
Release date:2002-02-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.854 Å)
Cite:Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
J.Mol.Biol., 316, 2002
1KHE
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1khe
PEPCK COMPLEX WITH NONHYDROLYZABLE GTP ANALOG, MAD DATA
Descriptor:Phosphoenolpyruvate Carboxykinase, cytosolic (GTP), PHOSPHOMETHYLPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Dunten, P., Belunis, C., Crowther, R., Hollfelder, K., Kammlott, U., Levin, W., Michel, H., Ramsey, G.B., Swain, A., Weber, D., Wertheimer, S.J.
Deposit date:2001-11-29
Release date:2002-02-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
J.Mol.Biol., 316, 2002
1KHF
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1khf
PEPCK COMPLEX WITH PEP
Descriptor:Phosphoenolpyruvate Carboxykinase, cytosolic (GTP) (E.C.4.1.1.3)
Authors:Dunten, P., Belunis, C., Crowther, R., Hollfelder, K., Kammlott, U., Levin, W., Michel, H., Ramsey, G.B., Swain, A., Weber, D., Wertheimer, S.J.
Deposit date:2001-11-29
Release date:2002-02-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
J.Mol.Biol., 316, 2002
1KHG
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1khg
PEPCK
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic (GTP) (E.C.4.1.1.32)
Authors:Dunten, P., Belunis, C., Crowther, R., Hollfelder, K., Kammlott, U., Levin, W., Michel, H., Ramsey, G.B., Swain, A., Weber, D., Wertheimer, S.J.
Deposit date:2001-11-29
Release date:2002-02-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
J.Mol.Biol., 316, 2002
1M51
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1m51
PEPCK COMPLEX WITH A GTP-COMPETITIVE INHIBITOR
Descriptor:Phosphoenolpyruvate Carboxykinase, cytosolic (E.C.4.1.1.32)
Authors:Foley, L.H., Wang, P., Dunten, P., Wertheimer, S.J.
Deposit date:2002-07-06
Release date:2003-09-30
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:X-ray Structures of two xanthine inhibitors bound to PEPCK and N-3 modifications of substituted 1,8-Dibenzylxanthines
Bioorg.Med.Chem.Lett., 13, 2003
1NHX
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1nhx
PEPCK COMPLEX WITH A GTP-COMPETITIVE INHIBITOR
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic (E.C.4.1.1.32)
Authors:Foley, L.H., Wang, P., Dunten, P., Ramsey, G., Gubler, M.-L., Wertheimer, S.J.
Deposit date:2002-12-19
Release date:2003-09-30
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-RAY STRUCTURES OF TWO XANTHINE INHIBITORS BOUND TO PEPCK and N-3 modifications of substituted 1,8-Dibenzylxanthines
Bioorg.Med.Chem.Lett., 13, 2003
2FAF
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2faf
THE STRUCTURE OF CHICKEN MITOCHONDRIAL PEPCK.
Descriptor:Phosphoenolpyruvate carboxykinase (E.C.4.1.1.32)
Authors:Holyoak, T., Sullivan, S.M., Nowak, T.
Deposit date:2005-12-07
Release date:2006-06-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Insights into the Mechanism of PEPCK Catalysis
Biochemistry, 45, 2006
2FAH
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2fah
THE STRUCTURE OF MITOCHONDRIAL PEPCK, COMPLEX WITH MN AND GDP
Descriptor:Phosphoenolpyruvate carboxykinase (E.C.4.1.1.32)
Authors:Holyoak, T., Sullivan, S.M., Nowak, T.
Deposit date:2005-12-07
Release date:2006-06-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Insights into the Mechanism of PEPCK Catalysis
Biochemistry, 45, 2006
2GMV
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2gmv
PEPCK COMPLEX WITH A GTP-COMPETITIVE INHIBITOR
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic (E.C.4.1.1.32)
Authors:Dunten, P.
Deposit date:2006-04-07
Release date:2007-05-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase.
Bioorg.Med.Chem.Lett., 17, 2007
2QEW
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2qew
RAT CYTOSOLIC PEPCK, IN COMPLEX WITH MANGANESE ION.
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Holyoak, T.
Deposit date:2007-06-26
Release date:2007-08-21
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid.
Biochemistry, 46, 2007
2QEY
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2qey
RAT CYTOSOLIC PEPCK IN COMPLEX WITH GTP
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Holyoak, T.
Deposit date:2007-06-26
Release date:2007-08-21
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid.
Biochemistry, 46, 2007
2QF1
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2qf1
RAT CYTOSOLIC PEPCK IN COMPLEX WITH OXALOACETIC ACID.
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Holyoak, T.
Deposit date:2007-06-26
Release date:2007-08-21
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid.
Biochemistry, 46, 2007
2QF2
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2qf2
RAT CYTOSOLIC PEPCK IN COMPLEX WITH OXALOACETIC ACID AND GDP.
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Holyoak, T.
Deposit date:2007-06-26
Release date:2007-08-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid.
Biochemistry, 46, 2007
2QZY
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2qzy
THE STRUCTURE OF CHICKEN MITOCHONDRIAL PEPCK IN COMPLEX WITH PEP
Descriptor:Phosphoenolpyruvate carboxykinase [GTP] (E.C.4.1.1.32)
Authors:Holyoak, T., Sullivan, S.M., Nowak, T.
Deposit date:2007-08-17
Release date:2007-09-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into the Mechanism of PEPCK Catalysis
Biochemistry, 45, 2006
2RK7
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2rk7
THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH OXALATE
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Stiffin, R.M., Carlson, G.M., Holyoak, T.
Deposit date:2007-10-16
Release date:2008-01-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition.
Biochemistry, 47, 2008
2RK8
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2rk8
THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH PHOSPHONOFORMATE
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Stiffin, R.M., Carlson, G.M., Holyoak, T.
Deposit date:2007-10-16
Release date:2008-01-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition.
Biochemistry, 47, 2008
2RKA
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2rka
THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH PHOSPHOGLYCOLATE
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Stiffin, R.M., Carlson, G.M., Holyoak, T.
Deposit date:2007-10-16
Release date:2008-01-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition.
Biochemistry, 47, 2008
2RKD
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2rkd
THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH 3-PHOSPHONOPROPIONATE
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Stiffin, R.M., Carlson, G.M., Holyoak, T.
Deposit date:2007-10-16
Release date:2008-01-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition.
Biochemistry, 47, 2008
2RKE
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2rke
THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH SULFOACETATE.
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Stiffin, R.M., Carlson, G.M., Holyoak, T.
Deposit date:2007-10-16
Release date:2008-01-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition.
Biochemistry, 47, 2008
2ZCI
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2zci
STRUCTURE OF A GTP-DEPENDENT BACTERIAL PEP-CARBOXYKINASE FROM CORYNEBACTERIUM GLUTAMICUM
Descriptor:Phosphoenolpyruvate carboxykinase [GTP] (E.C.4.1.1.32)
Authors:Aich, S., Prasad, L., Delbaere, L.T.J.
Deposit date:2007-11-09
Release date:2008-04-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a GTP-dependent bacterial PEP-carboxykinase from Corynebacterium glutamicum.
Int.J.Biochem.Cell Biol., 40, 2008
3DT2
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3dt2
THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH OXALATE AND GTP
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Holyoak, T.
Deposit date:2008-07-14
Release date:2008-08-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3DT4
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3dt4
THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH OXALATE AND GTP
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Holyoak, T.
Deposit date:2008-07-14
Release date:2008-08-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3DT7
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3dt7
THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH BETA-SULFOPYRUVATE AND GTP
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Holyoak, T.
Deposit date:2008-07-14
Release date:2008-08-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3DTB
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3dtb
THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH PHOSPHOGLYCOLATE AND GDP
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Sullivan, S.M., Holyoak, T.
Deposit date:2008-07-14
Release date:2008-08-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3MOE
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3moe
THE STRUCTURE OF RAT CYTOSOLIC PEPCK MUTANT A467G IN COMPLEX WITH BETA-SULFOPYRUVATE AND GTP
Descriptor:Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (E.C.4.1.1.32)
Authors:Johnson, T.A., Holyoak, T.
Deposit date:2010-04-22
Release date:2010-06-02
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Increasing the conformational entropy of the Omega-loop lid domain in phosphoenolpyruvate carboxykinase impairs catalysis and decreases catalytic fidelity .
Biochemistry, 49, 2010
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105025
entries available on 2014-11-19
00:00 UTC / 09:00 JST