1NHX

PEPCK COMPLEX WITH A GTP-COMPETITIVE INHIBITOR

Summary for 1NHX

• Entry DOI: 10.2210/pdb1nhx/pdb
• Related: 1KHB 1M51
• Descriptor: PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC, MANGANESE (II) ION, SODIUM ION, ... (7 entities in total)
• Functional Keywords: gluconeogenesis, xanthine, inhibitor, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P35558
• Total number of polymer chains: 1
• Total formula weight: 70363.31

Authors

Foley, L.H.,Wang, P.,Dunten, P.,Ramsey, G.,Gubler, M.-L.,Wertheimer, S.J. (deposition date: 2002-12-19, release date: 2003-09-30, Last modification date: 2024-02-14)

• Primary citation: FOLEY, L.H.,WANG, P.,DUNTEN, P.,RAMSEY, G.,GUBLER, M.-L.,WERTHEIMER, S.J.; X-RAY STRUCTURES OF TWO XANTHINE INHIBITORS BOUND TO PEPCK and N-3 modifications of substituted 1,8-Dibenzylxanthines; Bioorg.Med.Chem.Lett., 13:3871-3874, 2003; PubMed: 14552798; DOI: 10.1016/S0960-894X(03)00723-6

Experimental method

X-RAY DIFFRACTION (2.1 Å)