3MOE
The structure of rat cytosolic PEPCK mutant A467G in complex with Beta-Sulfopyruvate and GTP
Summary for 3MOE
| Entry DOI | 10.2210/pdb3moe/pdb |
| Related | 3MOF 3MOH |
| Descriptor | Phosphoenolpyruvate carboxykinase, cytosolic [GTP], GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... (8 entities in total) |
| Functional Keywords | kinase, gluconeogenesis, lyase |
| Biological source | Rattus norvegicus (brown rat,rat,rats) |
| Cellular location | Cytoplasm: P07379 |
| Total number of polymer chains | 1 |
| Total formula weight | 71417.04 |
| Authors | Johnson, T.A.,Holyoak, T. (deposition date: 2010-04-22, release date: 2010-06-02, Last modification date: 2024-02-21) |
| Primary citation | Johnson, T.A.,Holyoak, T. Increasing the conformational entropy of the Omega-loop lid domain in phosphoenolpyruvate carboxykinase impairs catalysis and decreases catalytic fidelity . Biochemistry, 49:5176-5187, 2010 Cited by PubMed: 20476774DOI: 10.1021/bi100399e PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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