3MOH

The structure of rat cytosolic PEPCK mutant A467G in complex with phosphoglycolate and GDP

Summary for 3MOH

Entry DOI	10.2210/pdb3moh/pdb
Related	3MOE 3MOF
Descriptor	Phosphoenolpyruvate carboxykinase, cytosolic [GTP], GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... (8 entities in total)
Functional Keywords	kinase, gluconeogenesis, lyase
Biological source	Rattus norvegicus (brown rat,rat,rats)
Cellular location	Cytoplasm: P07379
Total number of polymer chains	2
Total formula weight	141262.34
Authors	Johnson, T.A.,Holyoak, T. (deposition date: 2010-04-22, release date: 2010-06-02, Last modification date: 2024-02-21)
Primary citation	Johnson, T.A.,Holyoak, T. Increasing the conformational entropy of the Omega-loop lid domain in phosphoenolpyruvate carboxykinase impairs catalysis and decreases catalytic fidelity . Biochemistry, 49:5176-5187, 2010 Cited by PubMed: 20476774 DOI: 10.1021/bi100399e PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation