8TSM
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8SNP
| Crystal structure of mouse Netrin-1 in complex with samarium ions | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Heide, F, Legare, S, Stetefeld, J. | Deposit date: | 2023-04-27 | Release date: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Investigating the structural and functional roles of calcium binding in Netrin-1 To Be Published
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8S9P
| 1:1:1 agrin/LRP4/MuSK complex | Descriptor: | Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ... | Authors: | Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C. | Deposit date: | 2023-03-29 | Release date: | 2023-05-17 | Last modified: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex. Proc.Natl.Acad.Sci.USA, 120, 2023
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8HNA
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8HN0
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8EDK
| Structure of C. elegans UNC-6 LamN and EGF domains | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Netrin unc-6, ... | Authors: | Priest, J.M, Ozkan, E. | Deposit date: | 2022-09-04 | Release date: | 2023-01-11 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into the formation of repulsive netrin guidance complexes. Sci Adv, 10, 2024
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8DMK
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7NE1
| Structure of the complex between Netrin-1 and its receptor Neogenin | Descriptor: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. | Deposit date: | 2021-02-02 | Release date: | 2021-03-31 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184, 2021
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7NE0
| Structure of the ternary complex between Netrin-1, Repulsive-Guidance Molecule-B (RGMB) and Neogenin | Descriptor: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. | Deposit date: | 2021-02-02 | Release date: | 2021-03-31 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184, 2021
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7NDG
| Cryo-EM structure of the ternary complex between Netrin-1, Neogenin and Repulsive Guidance Molecule B | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neogenin, ... | Authors: | Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. | Deposit date: | 2021-02-01 | Release date: | 2021-03-31 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (5.98 Å) | Cite: | Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184, 2021
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7LRF
| Netrin-1 in complex with SOS | Descriptor: | 1,2-ETHANEDIOL, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... | Authors: | Gupta, M, McDougall, M, Torres, A.M, Stetefeld, J. | Deposit date: | 2021-02-16 | Release date: | 2022-02-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation. Nat Commun, 14, 2023
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7LER
| Netrin-1 filament assembly | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Netrin-1, ... | Authors: | McDougall, M, Gupta, M, Stetefeld, J. | Deposit date: | 2021-01-14 | Release date: | 2022-02-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (5.99 Å) | Cite: | The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation. Nat Commun, 14, 2023
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6FKQ
| THE CRYSTAL STRUCTURE OF A FRAGMENT OF NETRIN-1 IN COMPLEX WITH A FRAGMENT OF DRAXIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Bhowmick, T, Meijers, R. | Deposit date: | 2018-01-24 | Release date: | 2018-03-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC. Neuron, 97, 2018
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5LF2
| Crystal structure of laminin beta2 LE5-LF-LE6 | Descriptor: | CALCIUM ION, CHLORIDE ION, Laminin subunit beta-2 | Authors: | Pulido, D, Hohenester, E. | Deposit date: | 2016-06-30 | Release date: | 2016-07-27 | Last modified: | 2017-03-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystallographic analysis of the laminin beta 2 short arm reveals how the LF domain is inserted into a regular array of LE domains. Matrix Biol., 57-58, 2017
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4WNX
| Netrin 4 lacking the C-terminal Domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | McDougall, M, Patel, T, Reuten, R, Meier, M, Koch, M, Stetefeld, J. | Deposit date: | 2014-10-14 | Release date: | 2016-02-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.723 Å) | Cite: | Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes. Nat Commun, 7, 2016
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4URT
| The crystal structure of a fragment of netrin-1 in complex with FN5- FN6 of DCC | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Finci, L.I, Krueger, N, Sun, X, Zhang, J, Chegkazi, M, Wu, Y, Schenk, G, Mertens, H.D.T, Svergun, D.I, Zhang, Y, Wang, J.-h, Meijers, R. | Deposit date: | 2014-07-02 | Release date: | 2014-09-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The Crystal Structure of Netrin-1 in Complex with Dcc Reveals the Bi-Functionality of Netrin-1 as a Guidance Cue Neuron, 83, 2014
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4PLO
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4PLN
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4PLM
| Crystal Structure of Chicken Netrin-1 (LN-LE3) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Xu, K, Nikolov, D.B. | Deposit date: | 2014-05-18 | Release date: | 2014-06-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism. Science, 344, 2014
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4OVE
| X-ray Crystal Structure of Mouse Netrin-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Meier, M, Nikodemus, D, Reuten, R, Patel, T.R, Orriss, G, Okun, N, Koch, M, Stetefeld, J. | Deposit date: | 2014-02-21 | Release date: | 2015-02-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers. Cancer Cell, 29, 2016
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4AQT
| Laminin gamma1 LN-LE1-2 structure | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LAMININ SUBUNIT GAMMA-1, ... | Authors: | Carafoli, F, Hussain, S, Hohenester, E. | Deposit date: | 2012-04-19 | Release date: | 2012-08-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structures of the Network-Forming Short-Arm Tips of the Laminin Beta1 and Gamma1 Chains. Plos One, 7, 2012
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4AQS
| Laminin beta1 LN-LE1-4 structure | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LAMININ SUBUNIT BETA-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Carafoli, F, Hussain, S, Hohenester, E. | Deposit date: | 2012-04-19 | Release date: | 2012-08-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.109 Å) | Cite: | Crystal Structures of the Network-Forming Short-Arm Tips of the Laminin Beta1 and Gamma1 Chains. Plos One, 7, 2012
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3ZYJ
| NetrinG1 in complex with NGL1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C, ... | Authors: | Seiradake, E, Coles, C.H, Perestenko, P.V, Harlos, K, McIlhinney, R.A.J, Aricescu, A.R, Jones, E.Y. | Deposit date: | 2011-08-23 | Release date: | 2011-10-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structural Basis for Cell Surface Patterning Through Netring-Ngl Interactions. Embo J., 30, 2011
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3ZYI
| NetrinG2 in complex with NGL2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4, ... | Authors: | Seiradake, E, Coles, C.H, Perestenko, P.V, Harlos, K, McIlhinney, R.A.J, Aricescu, A.R, Jones, E.Y. | Deposit date: | 2011-08-23 | Release date: | 2011-10-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Basis for Cell Surface Patterning Through Netring-Ngl Interactions Embo J., 30, 2011
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3ZYG
| NETRING2 LAM AND EGF1 DOMAINS | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NETRIN-G2 | Authors: | Seiradake, E, Coles, C.H, Perestenko, P.V, Harlos, K, Mcilhinney, R.A.J, Aricescu, A.R, Jones, E.Y. | Deposit date: | 2011-08-22 | Release date: | 2011-10-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for Cell Surface Patterning Through Netring-Ngl Interactions. Embo J., 30, 2011
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