7LER

Netrin-1 filament assembly

This is a non-PDB format compatible entry.

Summary for 7LER

• Entry DOI: 10.2210/pdb7ler/pdb
• Descriptor: Netrin-1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: heparin binding protein, filament, signaling protein
• Biological source: Gallus gallus (Chicken)
• Total number of polymer chains: 8
• Total formula weight: 410860.53

Authors

McDougall, M.,Gupta, M.,Stetefeld, J. (deposition date: 2021-01-14, release date: 2022-02-23, Last modification date: 2023-10-25)

• Primary citation: Meier, M.,Gupta, M.,Akgul, S.,McDougall, M.,Imhof, T.,Nikodemus, D.,Reuten, R.,Moya-Torres, A.,To, V.,Ferens, F.,Heide, F.,Padilla-Meier, G.P.,Kukura, P.,Huang, W.,Gerisch, B.,Morgelin, M.,Poole, K.,Antebi, A.,Koch, M.,Stetefeld, J.; The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.; Nat Commun, 14:1226-1226, 2023; PubMed: 36869049; DOI: 10.1038/s41467-023-36692-w

Experimental method

X-RAY DIFFRACTION (5.99 Å)