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3GEF
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BU of 3gef by Molmil
Crystal structure of the R482W mutant of lamin A/C
Descriptor: Lamin-A/C
Authors:Magracheva, E, Kozlov, S, Stuart, C, Wlodawer, A, Zdanov, A.
Deposit date:2009-02-25
Release date:2009-08-04
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the lamin A/C R482W mutant responsible for dominant familial partial lipodystrophy (FPLD).
Acta Crystallogr.,Sect.F, 65, 2009
6JLB
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BU of 6jlb by Molmil
Crystal structure of lamin A/C fragment and assembly mechanisms of intermediate filaments
Descriptor: Lamin A/C
Authors:Ahn, J, Jo, I, Ha, N.C.
Deposit date:2019-03-04
Release date:2019-09-11
Method:X-RAY DIFFRACTION (3.205 Å)
Cite:Structural basis for lamin assembly at the molecular level.
Nat Commun, 10, 2019
7X5D
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BU of 7x5d by Molmil
Crystal Structure of the K316C mutant of Human Lamin A/C Coil 2 (residues 244-340)
Descriptor: Lamin-A/C
Authors:Ahn, J, Jo, I, Ha, N.-C.
Deposit date:2022-03-04
Release date:2023-03-08
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Atomic structure of the antiparallel four-helix bundle interactions for the formation of lamin filament
To Be Published
7YVD
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BU of 7yvd by Molmil
The crystal structure of the progerin C-terminal peptide and the Ig-like domain of lamin A/C
Descriptor: Lamin-A/C, SELENOCYSTEINE
Authors:Ahn, J, Ha, N.C.
Deposit date:2022-08-19
Release date:2023-08-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of the progerin C-terminal peptide and the Ig-like domain of lamin A/C
To Be Published
6RPR
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BU of 6rpr by Molmil
LEM domain of Emerin mutant T43I in complex with BAF dimer and the Igfold of the lamin A/C
Descriptor: LEM domain of emerin mutant T43I, Prelamin-A/C, SULFATE ION, ...
Authors:Essawy, N, Samson, C.
Deposit date:2019-05-14
Release date:2020-03-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:An Emerin LEM-Domain Mutation Impairs Cell Response to Mechanical Stress.
Cells, 8, 2019
6SNZ
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BU of 6snz by Molmil
Crystal structure of lamin A coil1b tetramer
Descriptor: GLYCEROL, Prelamin-A/C
Authors:Lilina, A.V, Chernyatina, A.A, Guzenko, D, Strelkov, S.V.
Deposit date:2019-08-28
Release date:2019-10-23
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Lateral A11type tetramerization in lamins.
J.Struct.Biol., 209, 2020
7CRG
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BU of 7crg by Molmil
Beta-strand-mediated dimeric formation of the extended Ig-like domains of human lamin A/C
Descriptor: Prelamin-A/C
Authors:Ahn, J, Ha, N.C.
Deposit date:2020-08-13
Release date:2021-08-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Beta-strand-mediated dimeric formation of the Ig-like domains of human lamin A/C and B1.
Biochem.Biophys.Res.Commun., 550, 2021
7D9N
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BU of 7d9n by Molmil
Crystal structure of a non-canonic progeria mutation S143F at lamin A/C and its structural implication to the premature aging
Descriptor: Lamin-A/C
Authors:Ahn, J, Jung, S, Ha, N.
Deposit date:2020-10-14
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal structure of progeria mutant S143F lamin A/C reveals increased hydrophobicity driving nuclear deformation.
Commun Biol, 5, 2022
6YF5
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BU of 6yf5 by Molmil
Lamin A 17-70 coil1A dimer stabilized by C-terminal capping
Descriptor: Prelamin-A/C,Microtubule-associated protein RP/EB family member 1
Authors:Lilina, A.V, Stalmans, G, Strelkov, S.V.
Deposit date:2020-03-26
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Addressing the Molecular Mechanism of Longitudinal Lamin Assembly Using Chimeric Fusions.
Cells, 9, 2020
6YJD
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BU of 6yjd by Molmil
Lamin A coil2 dimer stabilized by N-terminal capping
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Capsid assembly scaffolding protein,Prelamin-A/C, ...
Authors:Lilina, A.V, Stalmans, G, Strelkov, S.V.
Deposit date:2020-04-03
Release date:2021-02-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Addressing the Molecular Mechanism of Longitudinal Lamin Assembly Using Chimeric Fusions.
Cells, 9, 2020
3V5B
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BU of 3v5b by Molmil
Structure of Coil 2b of human lamin
Descriptor: Prelamin-A/C
Authors:Bollati, M, Bolognesi, M.
Deposit date:2011-12-16
Release date:2012-02-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of the lamin A/C R335W and E347K mutants: Implications for dilated cardiolaminopathies.
Biochem.Biophys.Res.Commun., 418, 2012
6YSH
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BU of 6ysh by Molmil
Lamin A 1-70 coil1A dimer stabilized by C-terminal capping
Descriptor: Prelamin-A/C,Microtubule-associated protein RP/EB family member 1
Authors:Stalmans, G, Lilina, A.V, Strelkov, S.V.
Deposit date:2020-04-22
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Addressing the Molecular Mechanism of Longitudinal Lamin Assembly Using Chimeric Fusions.
Cells, 9, 2020
3V4Q
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BU of 3v4q by Molmil
Structure of R335W mutant of human Lamin
Descriptor: Prelamin-A/C
Authors:Bollati, M, Bolognesi, M.
Deposit date:2011-12-15
Release date:2012-02-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Structures of the lamin A/C R335W and E347K mutants: Implications for dilated cardiolaminopathies.
Biochem.Biophys.Res.Commun., 418, 2012
3V4W
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BU of 3v4w by Molmil
Structure of E347K mutant of Lamin
Descriptor: Prelamin-A/C
Authors:Bollati, M, Bolognesi, M.
Deposit date:2011-12-15
Release date:2012-02-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structures of the lamin A/C R335W and E347K mutants: Implications for dilated cardiolaminopathies.
Biochem.Biophys.Res.Commun., 418, 2012
1X8Y
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BU of 1x8y by Molmil
Human lamin coil 2B
Descriptor: Lamin A/C
Authors:Strelkov, S.V, Schumacher, J, Burkhard, P, Aebi, U, Herrmann, H.
Deposit date:2004-08-19
Release date:2004-11-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the human lamin A coil 2B dimer: implications for the head-to-tail association of nuclear lamins
J.Mol.Biol., 343, 2004
1UFG
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BU of 1ufg by Molmil
Solution structure of immunoglobulin like domain of mouse nuclear lamin
Descriptor: Lamin A
Authors:Kobayashi, N, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-29
Release date:2004-06-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of immunoglobulin like domain of mouse nuclear lamin
To be Published
2XV5
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BU of 2xv5 by Molmil
Human lamin A coil 2B fragment
Descriptor: LAMIN-A/C
Authors:Kapinos, L.E, Burkhard, P, Aebi, U, Herrmann, H, Strelkov, S.V.
Deposit date:2010-10-22
Release date:2011-03-09
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Simultaneous Formation of Right- and Left-Handed Anti-Parallel Coiled-Coil Interfaces by a Coil2 Fragment of Human Lamin A.
J.Mol.Biol., 408, 2011
6GHD
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BU of 6ghd by Molmil
Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases
Descriptor: 1,2-ETHANEDIOL, Barrier-to-autointegration factor, Emerin, ...
Authors:Samson, C, Petitalot, A, Celli, F, Herrada, I, Ropars, V, Ledu, M.H, Nhiri, N, Arteni, A.A, Buendia, B, ZinnJustin, S.
Deposit date:2018-05-07
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases.
Nucleic Acids Res., 46, 2018
7Z21
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BU of 7z21 by Molmil
BAF A12T bound to the lamin A/C Ig-fold domain
Descriptor: Barrier-to-autointegration factor, N-terminally processed, CHLORIDE ION, ...
Authors:Marcelot, A, Legrand, P, Zinn-Justin, S.
Deposit date:2022-02-25
Release date:2022-08-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.629 Å)
Cite:The BAF A12T mutation disrupts lamin A/C interaction, impairing robust repair of nuclear envelope ruptures in Nestor-Guillermo progeria syndrome cells.
Nucleic Acids Res., 50, 2022
2YPT
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BU of 2ypt by Molmil
Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 mutant (E336A) in complex with a synthetic CSIM tetrapeptide from the C-terminus of prelamin A
Descriptor: CAAX PRENYL PROTEASE 1 HOMOLOG, PRELAMIN-A/C, ZINC ION
Authors:Pike, A.C.W, Dong, Y.Y, Quigley, A, Dong, L, Savitsky, P, Cooper, C.D.O, Chaikuad, A, Goubin, S, Shrestha, L, Li, Q, Mukhopadhyay, S, Yang, J, Xia, X, Shintre, C.A, Barr, A.J, Berridge, G, Chalk, R, Bray, J.E, von Delft, F, Bullock, A, Bountra, C, Arrowsmith, C.H, Edwards, A, Burgess-Brown, N, Carpenter, E.P.
Deposit date:2012-11-01
Release date:2012-12-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The Structural Basis of Zmpste24-Dependent Laminopathies.
Science, 339, 2013
1IFR
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BU of 1ifr by Molmil
Structure of Lamin A/C Globular Domain
Descriptor: GLYCEROL, Lamin A/C
Authors:Dhe-Paganon, S, Werner, E.D, Shoelson, S.E.
Deposit date:2001-04-13
Release date:2002-07-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of the globular tail of nuclear lamin.
J.Biol.Chem., 277, 2002

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