PDB: 16 resultsInfo pagesStatus searchChemie searchBIRD

---

3GA0	CtBP1/BARS Gly172->Glu mutant structure: impairing NAD(H) binding and dimerization Descriptor: C-terminal-binding protein 1, FORMIC ACID Authors: Nardini, M, Valente, C, Ricagno, S, Luini, A, Corda, D, Bolognesi, M. Deposit date: 2009-02-16 Release date: 2009-04-21 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.4 Å) Cite: CtBP1/BARS Gly172-->Glu mutant structure: impairing NAD(H)-binding and dimerization Biochem.Biophys.Res.Commun., 381, 2009
8ARI	Cryo-EM structure of human CtBP1/RAI2(303-362) delta(331-341) filament Descriptor: C-terminal-binding protein 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Retinoic acid-induced protein 2 Authors: Mullapudi, E, Goradia, N, Wilmanns, M. Deposit date: 2022-08-16 Release date: 2023-08-23 Method: ELECTRON MICROSCOPY (3 Å) Cite: Cryo-EM structure of human CtBP1/RAI2(303-362) delta(331-341) filament To Be Published
7KWM	CtBP1 (28-375) L182F/V185T - AMP Descriptor: ADENOSINE MONOPHOSPHATE, C-terminal-binding protein 1, CALCIUM ION Authors: Royer, W.E, Del Campo, M. Deposit date: 2020-12-01 Release date: 2021-02-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP). J.Biol.Chem., 296, 2021
4LCE	CtBP1 in complex with substrate MTOB Descriptor: 4-(METHYLSULFANYL)-2-OXOBUTANOIC ACID, C-terminal-binding protein 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Hilbert, B.J, Schiffer, C.A, Royer Jr, W.E. Deposit date: 2013-06-21 Release date: 2014-03-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design. Febs Lett., 588, 2014
6CDF	Human CtBP1 (28-378) Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, C-terminal-binding protein 1, CALCIUM ION, ... Authors: Royer, W.E, Bellesis, A.G. Deposit date: 2018-02-08 Release date: 2018-05-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Assembly of human C-terminal binding protein (CtBP) into tetramers. J. Biol. Chem., 293, 2018
6CDR	Human CtBP1 (28-378) Descriptor: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, C-terminal-binding protein 1, ... Authors: Royer, W.E, Bellesis, A.G. Deposit date: 2018-02-09 Release date: 2018-05-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.399 Å) Cite: Assembly of human C-terminal binding protein (CtBP) into tetramers. J. Biol. Chem., 293, 2018
6V8A	Human CtBP1 (28-375) in complex with AMP Descriptor: ADENOSINE MONOPHOSPHATE, C-terminal-binding protein 1, CALCIUM ION, ... Authors: Royer, W.E. Deposit date: 2019-12-10 Release date: 2021-02-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.35 Å) Cite: NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP). J.Biol.Chem., 296, 2021
6V89	Human CtBP1 (28-375) in complex with AMP Descriptor: ADENOSINE MONOPHOSPHATE, C-terminal-binding protein 1, CALCIUM ION, ... Authors: Royer, W.E. Deposit date: 2019-12-10 Release date: 2021-02-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.45 Å) Cite: NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP). J.Biol.Chem., 296, 2021
4U6S	CtBP1 in complex with substrate phenylpyruvate Descriptor: 3-PHENYLPYRUVIC ACID, C-terminal-binding protein 1, CALCIUM ION, ... Authors: Hilbert, B.J, Morris, B.L, Ellis, K.C, Paulsen, J.L, Schiffer, C.A, Grossman, S.R, Royer Jr, W.E. Deposit date: 2014-07-29 Release date: 2015-02-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure-Guided Design of a High Affinity Inhibitor to Human CtBP. Acs Chem.Biol., 10, 2015
4U6Q	CtBP1 bound to inhibitor 2-(hydroxyimino)-3-phenylpropanoic acid Descriptor: (2E)-2-(hydroxyimino)-3-phenylpropanoic acid, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, C-terminal-binding protein 1, ... Authors: Hilbert, B.J, Morris, B.L, Ellis, K.C, Paulsen, J.L, Schiffer, C.A, Grossman, S.R, Royer Jr, W.E. Deposit date: 2014-07-29 Release date: 2015-02-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-Guided Design of a High Affinity Inhibitor to Human CtBP. Acs Chem.Biol., 10, 2015
2HU2	CTBP/BARS in ternary complex with NAD(H) and RRTGAPPAL peptide Descriptor: 9-mer peptide from Zinc finger protein 217, C-terminal-binding protein 1, FORMIC ACID, ... Authors: Nardini, M, Bolognesi, M, Quinlan, K.G.R, Verger, A, Francescato, P, Crossley, M. Deposit date: 2006-07-26 Release date: 2006-10-31 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Specific Recognition of ZNF217 and Other Zinc Finger Proteins at a Surface Groove of C-Terminal Binding Proteins Mol.Cell.Biol., 26, 2006
1MX3	Crystal structure of CtBP dehydrogenase core holo form Descriptor: ACETIC ACID, C-terminal binding protein 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Kumar, V, Carlson, J.E, Ohgi, K.E, Edwards, T.E, Rose, D.W, Escalante, C.R, Aggarwal, A.K. Deposit date: 2002-10-01 Release date: 2002-12-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Transcription Corepressor CtBP Is an NAD+-Regulated Dehydrogenase Mol.Cell, 10, 2002
1HKU	CtBP/BARS: a dual-function protein involved in transcription corepression and Golgi membrane fission Descriptor: C-TERMINAL BINDING PROTEIN 3, FORMIC ACID, GLYCEROL, ... Authors: Nardini, M, Spano, S, Cericola, C, Pesce, A, Massaro, A, Millo, E, Luini, A, Corda, D, Bolognesi, M. Deposit date: 2003-03-11 Release date: 2003-06-19 Last modified: 2016-12-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Ctbp/Bars: A Dual-Function Protein Involved in Transcription Co-Repression and Golgi Membrane Fission Embo J., 22, 2003
1HL3	CtBP/BARS in ternary complex with NAD(H) and PIDLSKK peptide Descriptor: C-TERMINAL BINDING PROTEIN 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PRO-ILE-ASP-LEU-SER-LYS-LYS PEPTIDE Authors: Nardini, M, Spano, S, Cericola, C, Pesce, A, Massaro, A, Millo, E, Luini, A, Corda, D, Bolognesi, M. Deposit date: 2003-03-13 Release date: 2003-06-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Ctbp/Bars: A Dual-Function Protein Involved in Transcription Co-Repression and Golgi Membrane Fission Embo J., 22, 2003
4LCJ	CtBP2 in complex with substrate MTOB Descriptor: 4-(METHYLSULFANYL)-2-OXOBUTANOIC ACID, C-terminal-binding protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Hilbert, B.J, Schiffer, C.A, Royer Jr, W.E. Deposit date: 2013-06-21 Release date: 2014-03-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.86 Å) Cite: Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design. Febs Lett., 588, 2014
6WKW	EM structure of CtBP2 with a minimal dehydrogenase domain of CtBP2 Descriptor: C-terminal-binding protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Jecrois, A.M. Deposit date: 2020-04-17 Release date: 2020-12-02 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Cryo-EM structure of CtBP2 confirms tetrameric architecture. Structure, 29, 2021