4LCE

CtBP1 in complex with substrate MTOB

Summary for 4LCE

Entry DOI	10.2210/pdb4lce/pdb
Related	4LCJ
Descriptor	C-terminal-binding protein 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-(METHYLSULFANYL)-2-OXOBUTANOIC ACID, ... (4 entities in total)
Functional Keywords	rossmann fold, transcriptional co-repressor, d-isomer 2-hydroxyacid dehydrogenase, oxidoreductase-oxidoreductase substrate complex, oxidoreductase/oxidoreductase substrate
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : Q13363
Total number of polymer chains	1
Total formula weight	38951.07
Authors	Hilbert, B.J.,Schiffer, C.A.,Royer Jr., W.E. (deposition date: 2013-06-21, release date: 2014-03-19, Last modification date: 2024-02-28)
Primary citation	Hilbert, B.J.,Grossmann, S.R.,Schiffer, C.A.,Royer, W.E. Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design. Febs Lett., 588:1743-1748, 2014 Cited by PubMed: 24657618 DOI: 10.1016/j.febslet.2014.03.026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.38 Å)

Structure validation