4LCJ

CtBP2 in complex with substrate MTOB

Summary for 4LCJ

• Entry DOI: 10.2210/pdb4lcj/pdb
• Related: 4LCE
• Descriptor: C-terminal-binding protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-(METHYLSULFANYL)-2-OXOBUTANOIC ACID, ... (4 entities in total)
• Functional Keywords: rossmann fold, transcriptional corepressor, d-isomer 2-hydroxyacid dehydrogenase, oxidoreductase-oxidoreductase substrate complex, oxidoreductase/oxidoreductase substrate
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : P56545
• Total number of polymer chains: 8
• Total formula weight: 314651.46

Authors

Hilbert, B.J.,Schiffer, C.A.,Royer Jr., W.E. (deposition date: 2013-06-21, release date: 2014-03-19, Last modification date: 2024-02-28)

• Primary citation: Hilbert, B.J.,Grossmann, S.R.,Schiffer, C.A.,Royer, W.E.; Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design.; Febs Lett., 588:1743-1748, 2014; PubMed: 24657618; DOI: 10.1016/j.febslet.2014.03.026

Experimental method

X-RAY DIFFRACTION (2.86 Å)