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1K3Z
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X-ray crystal structure of the IkBb/NF-kB p65 homodimer complex
Descriptor: Transcription factor p65, transcription factor inhibitor I-kappa-B-beta
Authors:Shiva, M, Huang, D.B, Chen, Y, Huxford, T, Ghosh, S, Ghosh, G.
Deposit date:2001-10-04
Release date:2002-10-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex.
J.Biol.Chem., 278, 2003
1YYH
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BU of 1yyh by Molmil
Crystal structure of the human Notch 1 ankyrin domain
Descriptor: Notch 1, ankyrin domain
Authors:Ehebauer, M.T, Chirgadze, D.Y, Hayward, P, Martinez-Arias, A, Blundell, T.L.
Deposit date:2005-02-25
Release date:2005-08-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:High-resolution crystal structure of the human Notch 1 ankyrin domain
Biochem.J., 392, 2005
6JD6
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BU of 6jd6 by Molmil
An ankyrin-repeat protein complex guides cargos from inner envelope to thylakoid Tat pathway
Descriptor: Ankyrin repeat domain-containing protein EMB506, chloroplastic, Ankyrin repeat domain-containing protein, ...
Authors:Ouyang, M, Zhang, L.X.
Deposit date:2019-01-31
Release date:2020-02-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An ankyrin-repeat protein complex guides cargos from inner envelope to thylakoid Tat pathway
To Be Published
6L93
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BU of 6l93 by Molmil
X-ray structure of the ligand-free human TRPV1 ankyrin repeat domain
Descriptor: Transient receptor potential cation channel subfamily V member 1
Authors:Tanaka, M, Hayakawa, K, Unno, M.
Deposit date:2019-11-08
Release date:2020-03-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.47 Å)
Cite:Structure determination of the human TRPV1 ankyrin-repeat domain under nonreducing conditions.
Acta Crystallogr.,Sect.F, 76, 2020
6LGP
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BU of 6lgp by Molmil
cryo-EM structure of TRPV3 in lipid nanodisc
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, DIUNDECYL PHOSPHATIDYL CHOLINE, Transient receptor potential cation channel subfamily V member 3
Authors:Shimada, H, Kusakizako, T, Nishizawa, T, Nureki, O.
Deposit date:2019-12-05
Release date:2020-06-24
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism.
Nat.Struct.Mol.Biol., 27, 2020
6JZO
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BU of 6jzo by Molmil
Structure of the mouse TRPC4 ion channel
Descriptor: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ...
Authors:Duan, J, Li, Z, Li, J, Zhang, J.
Deposit date:2019-05-03
Release date:2020-10-21
Last modified:2021-05-05
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structure of the mouse TRPC4 ion channel
To Be Published
6MHS
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BU of 6mhs by Molmil
Structure of the human TRPV3 channel in a putative sensitized conformation
Descriptor: Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHX
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BU of 6mhx by Molmil
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (2)
Descriptor: Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
8V6K
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BU of 8v6k by Molmil
Apo-state cryo-EM structure of human TRPV3 in cNW30 nanodiscs
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
Authors:Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
Deposit date:2023-12-01
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.46 Å)
Cite:TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Sci Adv, 10, 2024
8V6N
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BU of 8v6n by Molmil
Open-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-aminoethyl diphenylborinate, ARACHIDONIC ACID, ...
Authors:Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
Deposit date:2023-12-01
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.59 Å)
Cite:TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Sci Adv, 10, 2024
8X94
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BU of 8x94 by Molmil
Structure of human TRPV1 in complex with antagonist --protein purified without CHS
Descriptor: 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile, CHOLESTEROL, Transient receptor potential cation channel subfamily V member 1,Green fluorescent protein
Authors:Fan, J, Lei, X.
Deposit date:2023-11-29
Release date:2024-08-14
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Structural basis of TRPV1 inhibition by SAF312 and cholesterol.
Nat Commun, 15, 2024
7FCV
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BU of 7fcv by Molmil
Cryo-EM structure of the Potassium channel AKT1 mutant from Arabidopsis thaliana
Descriptor: PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1
Authors:Yang, G.H, Lu, Y.M, Jia, Y.T, Zhang, Y.M, Tang, R.F, Xu, X, Li, X.M, Lei, J.L.
Deposit date:2021-07-15
Release date:2022-11-09
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Nat Commun, 13, 2022
8WUI
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BU of 8wui by Molmil
SKOR D312N L271P double mutation
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Potassium channel SKOR
Authors:Gao, X, Sun, T, Lu, Y, Jia, Y, Xu, X, Zhang, Y, Fu, P, Yang, G.
Deposit date:2023-10-20
Release date:2024-04-10
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural changes in the conversion of an Arabidopsis outward-rectifying K + channel into an inward-rectifying channel.
Plant Commun., 5, 2024
8WTZ
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BU of 8wtz by Molmil
potassium outward rectifier channel SKOR
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Potassium channel SKOR
Authors:Gao, X, Sun, T, Lu, Y, Jia, Y, Xu, X, Zhang, Y, Fu, P, Yang, G.
Deposit date:2023-10-19
Release date:2024-04-10
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural changes in the conversion of an Arabidopsis outward-rectifying K + channel into an inward-rectifying channel.
Plant Commun., 5, 2024
8V6L
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BU of 8v6l by Molmil
Open-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Tetrahydrocannabivarin, ...
Authors:Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
Deposit date:2023-12-01
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Sci Adv, 10, 2024
8V6O
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BU of 8v6o by Molmil
Inactivated-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-aminoethyl diphenylborinate, SODIUM ION, ...
Authors:Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
Deposit date:2023-12-01
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Sci Adv, 10, 2024
8V6M
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BU of 8v6m by Molmil
Inactivated-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Tetrahydrocannabivarin, ...
Authors:Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
Deposit date:2023-12-01
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Sci Adv, 10, 2024
7K4F
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BU of 7k4f by Molmil
Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor 31
Descriptor: 5-[(4-{cis-4-[3-(trifluoromethyl)phenyl]cyclohexyl}piperazin-1-yl)methyl]pyridin-2(1H)-one, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
Authors:Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I.
Deposit date:2020-09-15
Release date:2020-12-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
7K4D
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BU of 7k4d by Molmil
Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor 3OG
Descriptor: 5-[(4-{trans-4-hydroxy-4-[3-(trifluoromethyl)phenyl]cyclohexyl}piperazin-1-yl)methyl]pyridin-2(1H)-one, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
Authors:Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I.
Deposit date:2020-09-15
Release date:2020-12-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
7K4B
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BU of 7k4b by Molmil
Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor cis-22a
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[cis-4-(3-methylphenyl)cyclohexyl]-4-(pyridin-3-yl)piperazine, CALCIUM ION, ...
Authors:Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I.
Deposit date:2020-09-15
Release date:2020-12-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
7K4C
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BU of 7k4c by Molmil
Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor Br-cis-22a
Descriptor: 1-(5-bromopyridin-3-yl)-4-[cis-4-(3-methylphenyl)cyclohexyl]piperazine, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
Authors:Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I.
Deposit date:2020-09-15
Release date:2020-12-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
3J5P
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BU of 3j5p by Molmil
Structure of TRPV1 ion channel determined by single particle electron cryo-microscopy
Descriptor: Transient receptor potential cation channel subfamily V member 1
Authors:Liao, M, Cao, E, Julius, D, Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.275 Å)
Cite:Structure of the TRPV1 ion channel determined by electron cryo-microscopy.
Nature, 504, 2013
7K4E
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BU of 7k4e by Molmil
Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor 30
Descriptor: 5-({4-[(1R,4S)-3'-methyl[1,2,3,4-tetrahydro[1,1'-biphenyl]]-4-yl]piperazin-1-yl}methyl)pyridin-2(1H)-one, Transient receptor potential cation channel subfamily V member 6
Authors:Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I.
Deposit date:2020-09-15
Release date:2020-12-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
7K4A
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BU of 7k4a by Molmil
Cryo-EM structure of human TRPV6 in the open state
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ...
Authors:Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I.
Deposit date:2020-09-15
Release date:2020-12-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
3J9J
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BU of 3j9j by Molmil
Structure of the capsaicin receptor, TRPV1, determined by single particle electron cryo-microscopy
Descriptor: Transient receptor potential cation channel subfamily V member 1
Authors:Wang, R.Y.-R, Barad, B.A, Fraser, J.S, DiMaio, F.
Deposit date:2015-02-02
Release date:2015-09-02
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.275 Å)
Cite:EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.
Nat.Methods, 12, 2015

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