8V6K

Apo-state cryo-EM structure of human TRPV3 in cNW30 nanodiscs

Summary for 8V6K

Entry DOI	10.2210/pdb8v6k/pdb
EMDB information	42994
Descriptor	Transient receptor potential cation channel subfamily V member 3, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, ... (4 entities in total)
Functional Keywords	transient receptor potential v family member 3, trp, channel, trpv3, trp channels, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	395134.46
Authors	Nadezhdin, K.D.,Neuberger, A.,Sobolevsky, A.I. (deposition date: 2023-12-01, release date: 2024-04-17, Last modification date: 2024-05-08)
Primary citation	Nadezhdin, K.D.,Neuberger, A.,Khosrof, L.S.,Talyzina, I.A.,Khau, J.,Yelshanskaya, M.V.,Sobolevsky, A.I. TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. Sci Adv, 10:eadn2453-eadn2453, 2024 Cited by PubMed: 38691614 DOI: 10.1126/sciadv.adn2453 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.46 Å)

Structure validation