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4CT5
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BU of 4ct5 by Molmil
DDX6
Descriptor: ACETATE ION, DDX6
Authors:Ozgur, S, Basquin, J, Conti, E.
Deposit date:2014-03-12
Release date:2014-05-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression.
Mol.Cell, 54, 2014
5XDR
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BU of 5xdr by Molmil
Crystal structure of human DEAH-box RNA helicase DHX15 in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15, ...
Authors:Murakami, K, Nakano, K, Shimizu, T, Ohto, U.
Deposit date:2017-03-29
Release date:2017-06-21
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of human DEAH-box RNA helicase 15 reveals a domain organization of the mammalian DEAH/RHA family
Acta Crystallogr F Struct Biol Commun, 73, 2017
6O16
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BU of 6o16 by Molmil
Crystal structure of murine DHX37 in complex with RNA
Descriptor: DEAH (Asp-Glu-Ala-His) box polypeptide 37, RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3')
Authors:Boneberg, F, Brandmann, T, Kobel, L, van den Heuvel, J, Bargsten, K, Bammert, L, Kutay, U, Jinek, M.
Deposit date:2019-02-18
Release date:2019-04-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.875 Å)
Cite:Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis.
Rna, 25, 2019
6O5F
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BU of 6o5f by Molmil
Crystal structure of DEAD-box RNA helicase DDX3X at pre-unwound state
Descriptor: ATP-dependent RNA helicase DDX3X, CHLORIDE ION, RNA (5'-R(P*CP*AP*AP*GP*GP*UP*CP*AP*UP*UP*CP*GP*CP*AP*AP*GP*AP*GP*UP*GP*GP*CP*C)-3')
Authors:Song, H, Ji, X.
Deposit date:2019-03-02
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:The mechanism of RNA duplex recognition and unwinding by DEAD-box helicase DDX3X.
Nat Commun, 10, 2019
5SUQ
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BU of 5suq by Molmil
Crystal structure of the THO-Sub2 complex
Descriptor: 12-TUNGSTOPHOSPHATE, ATP-dependent RNA helicase SUB2, Tex1, ...
Authors:Ren, Y, Blobel, G.
Deposit date:2016-08-03
Release date:2017-01-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (6 Å)
Cite:Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1.
Elife, 6, 2017
5SUP
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BU of 5sup by Molmil
Crystal structure of the Sub2-Yra1 complex in association with RNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase SUB2, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Ren, Y, Schmiege, P, Blobel, G.
Deposit date:2016-08-03
Release date:2017-01-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1.
Elife, 6, 2017
2EYQ
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BU of 2eyq by Molmil
Crystal structure of Escherichia coli transcription-repair coupling factor
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, Transcription-repair coupling factor
Authors:Deaconescu, A.M, Darst, S.A.
Deposit date:2005-11-09
Release date:2006-02-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for bacterial transcription-coupled DNA repair.
Cell(Cambridge,Mass.), 124, 2006
7R2K
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BU of 7r2k by Molmil
elongated Cascade complex from type I-A CRISPR-Cas system
Descriptor: CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ...
Authors:Hu, C, Ni, D, Nam, K.H, Terns, M, Stahlberg, H, Ke, A.
Deposit date:2022-02-04
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural snapshots for an atypic type I CRISPR-Cas system
To Be Published
9BPA
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BU of 9bpa by Molmil
Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, tetramer form
Descriptor: (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta
Authors:Ito, F, Li, Z, Chen, X.S.
Deposit date:2024-05-07
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM.
Nat Commun, 15, 2024
9BP9
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BU of 9bp9 by Molmil
Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, dimer form
Descriptor: (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta
Authors:Ito, F, Li, Z, Chen, X.S.
Deposit date:2024-05-07
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM.
Nat Commun, 15, 2024
3SQW
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BU of 3sqw by Molmil
Structure of Mss116p (NTE deletion) bound to ssRNA and AMP-PNP
Descriptor: ATP-dependent RNA helicase MSS116, mitochondrial, MAGNESIUM ION, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2011-07-06
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.909 Å)
Cite:High-Throughput Genetic Identification of Functionally Important Regions of the Yeast DEAD-Box Protein Mss116p.
J.Mol.Biol., 413, 2011
3KX2
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BU of 3kx2 by Molmil
Crystal structure of Prp43p in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43
Authors:Nielsen, K.H, Andersen, G.R, He, Y.
Deposit date:2009-12-02
Release date:2010-01-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the function of DEAH helicases
Embo Rep., 11, 2010
5M5P
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BU of 5m5p by Molmil
S. cerevisiae spliceosomal helicase Brr2 (271-end) in complex with the Jab/MPN domain of S. cerevisiae Prp8
Descriptor: Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2
Authors:Becke, C, Absmeier, E, Wollenhaupt, J, Santos, K.F, Wahl, M.C.
Deposit date:2016-10-22
Release date:2016-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2.
Cell Cycle, 16, 2017
2XAU
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BU of 2xau by Molmil
Crystal structure of the Prp43p DEAH-box RNA helicase in complex with ADP
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
Authors:Walbott, H, Mouffok, S, Capeyrou, R, Lebaron, S, van Tilbeurgh, H, Henry, Y, Leulliot, N.
Deposit date:2010-03-31
Release date:2010-06-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Prp43P Contains a Processive Helicase Structural Architecture with a Specific Regulatory Domain.
Embo J., 29, 2010
2XGJ
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BU of 2xgj by Molmil
Structure of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT RNA HELICASE DOB1, RNA (5'-(*AP*AP*AP*AP*A)-3')
Authors:Weir, J.R, Bonneau, F, Hentschel, J, Conti, E.
Deposit date:2010-06-04
Release date:2010-06-23
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Analysis Reveals the Characteristic Features of Mtr4, a Dexh Helicase Involved in Nuclear RNA Processing and Surveillance.
Proc.Natl.Acad.Sci.USA, 107, 2010
1S2M
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BU of 1s2m by Molmil
Crystal Structure of the DEAD box protein Dhh1p
Descriptor: Putative ATP-dependent RNA helicase DHH1
Authors:Cheng, Z, Song, H.
Deposit date:2004-01-09
Release date:2005-03-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure and functional analysis of DEAD-box protein Dhh1p.
Rna, 11, 2005
4KBG
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BU of 4kbg by Molmil
almost closed conformation of the helicase core of the RNA helicase Hera
Descriptor: Heat resistant RNA dependent ATPase, SULFATE ION
Authors:Rudolph, M.G, Klostermeier, D.
Deposit date:2013-04-23
Release date:2013-07-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Rearranging RNA structures at 75C? toward the molecular mechanism and physiological function of the thermus thermophilus DEAD-box helicase hera.
Biopolymers, 99, 2013
4KBF
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BU of 4kbf by Molmil
two different open conformations of the helicase core of the RNA helicase Hera
Descriptor: ADENOSINE MONOPHOSPHATE, Heat resistant RNA dependent ATPase, SODIUM ION, ...
Authors:Rudolph, M.G, Klostermeier, D.
Deposit date:2013-04-23
Release date:2013-07-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rearranging RNA structures at 75C? toward the molecular mechanism and physiological function of the thermus thermophilus DEAD-box helicase hera.
Biopolymers, 99, 2013
3TBK
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BU of 3tbk by Molmil
Mouse RIG-I ATPase Domain
Descriptor: 1,2-ETHANEDIOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RIG-I Helicase Domain
Authors:Civril, F, Bennett, M.D, Hopfner, K.-P.
Deposit date:2011-08-07
Release date:2011-10-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling.
Embo Rep., 12, 2011
1OYW
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BU of 1oyw by Molmil
Structure of the RecQ Catalytic Core
Descriptor: ATP-dependent DNA helicase, MANGANESE (II) ION, ZINC ION
Authors:Bernstein, D.A, Zittel, M.C, Keck, J.L.
Deposit date:2003-04-07
Release date:2003-10-07
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-resolution structure of the E. coli RecQ helicase catalytic core
Embo J., 22, 2003
1OYY
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BU of 1oyy by Molmil
Structure of the RecQ Catalytic Core bound to ATP-gamma-S
Descriptor: ATP-dependent DNA helicase, MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Bernstein, D.A, Zittel, M.C, Keck, J.L.
Deposit date:2003-04-07
Release date:2003-10-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:High-resolution structure of the E. coli RecQ helicase catalytic core
Embo J., 22, 2003
4KIT
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BU of 4kit by Molmil
Crystal structure of human Brr2 in complex with the Prp8 Jab1/MPN domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, ...
Authors:Wahl, M.C, Wandersleben, T, Santos, K.F.
Deposit date:2013-05-02
Release date:2013-06-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.598 Å)
Cite:Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8.
Science, 341, 2013
3SQX
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BU of 3sqx by Molmil
Structure of Mss116p (NTE and C-tail double deletion) bound to ssRNA and AMP-PNP
Descriptor: ATP-dependent RNA helicase MSS116, mitochondrial, MAGNESIUM ION, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2011-07-06
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.112 Å)
Cite:High-Throughput Genetic Identification of Functionally Important Regions of the Yeast DEAD-Box Protein Mss116p.
J.Mol.Biol., 413, 2011
2V1X
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BU of 2v1x by Molmil
Crystal structure of human RECQ-like DNA helicase
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT DNA HELICASE Q1, ...
Authors:Pike, A.C.W, Shrestha, B, Burgess-Brown, N, King, O, Ugochukwu, E, Watt, S, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Gileadi, O.
Deposit date:2007-05-30
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Human Recq1 Helicase Reveals a Putative Strand-Separation Pin.
Proc.Natl.Acad.Sci.USA, 106, 2009
2VSX
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BU of 2vsx by Molmil
Crystal Structure of a Translation Initiation Complex
Descriptor: ADENOSINE MONOPHOSPHATE, ATP-DEPENDENT RNA HELICASE EIF4A, EUKARYOTIC INITIATION FACTOR 4F SUBUNIT P150
Authors:Schutz, P, Bumann, M, Oberholzer, A.E, Bieniossek, C, Altmann, M, Trachsel, H, Baumann, U.
Deposit date:2008-04-30
Release date:2008-06-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the Yeast Eif4A-Eif4G Complex: An RNA-Helicase Controlled by Protein-Protein Interactions.
Proc.Natl.Acad.Sci.USA, 105, 2008

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